2002
DOI: 10.5326/0380176
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Spontaneous Gastroduodenal Perforation in 16 Dogs and Seven Cats (1982–1999)

Abstract: The records of 23 dogs and cats diagnosed with spontaneous gastroduodenal perforation (GDP) were retrospectively reviewed. Survival was 63% in dogs and 14% in cats. Rottweilers <5 years of age were overrepresented. Clinical evidence of gastrointestinal bleeding was common in dogs but not in cats. Shock was an uncommon presenting condition in dogs and was not closely linked to outcome. In fact, progression of an ulcerating lesion to GDP was not associated with marked changes in symptoms exhibited by many patien… Show more

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Cited by 81 publications
(109 citation statements)
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“…14-16 While less common, masses, both benign and neoplastic as well as a variety of inflammatory lesions of the duodenum have been reported in the literature. [17][18][19][20][21][22][23] Positional survey radiography may provide an inexpensive, readily available method for further evaluating some of these lesions.…”
Section: Discussionmentioning
confidence: 99%
“…14-16 While less common, masses, both benign and neoplastic as well as a variety of inflammatory lesions of the duodenum have been reported in the literature. [17][18][19][20][21][22][23] Positional survey radiography may provide an inexpensive, readily available method for further evaluating some of these lesions.…”
Section: Discussionmentioning
confidence: 99%
“…In dogs and other animals, peritonitis due to ruptures associated with intestinal ulcers is a common clinical finding (Hinton et al 2002;Case et al 2010). However, intestinal tumours generally appear radiographically as masses that are narrowing or obstructing the intestinal lumen (Hurov 1962;Head et al 2002).…”
Section: Discussionmentioning
confidence: 99%
“…There is also a direct effect on gastric epithelial cells, whereby NSAIDs are trapped by pH gradient changes and lead to cell necrosis (Fig 2b) (Singh and Triadafilopoulos 1999, Matz and Guilford 2003). Clinical signs vary and are often undetectable via history and examination alone (Hinton and others 2002). Common significant effects are vomiting (with or without haemorrhage), melaena and anorexia (Lascelles and others 2005, Monteiro-Steagall and others 2013), but more severe manifestations include peritonitis and GI necrosis, and may ultimately result in death or euthanasia (Stanton and Bright 1989).…”
Section: Impact Of Nsaids On the Gi Tractmentioning
confidence: 99%