Spontaneous Fungal Peritonitis

González-Cordero, Ariel; Malavé-Sánchez, Melanie; Vergara-Gómez, Mark A.; Franqui-Rivera, Hilton

doi:10.1016/j.jaccas.2019.07.036

Cited by 1 publication

(1 citation statement)

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“…Given the pathogenic gut flora and increased intestinal permeability, we consider that cardiac dysfunction may be a risk factor for the development of PD-related peritonitis. Previously, there have been three case reports regarding acute peritonitis in patients not undergoing dialysis complicated with heart failure 44 – 46 , which supported our hypothesis.…”

Section: Discussionsupporting

confidence: 83%

Association between reduced left ventricular ejection fraction and peritoneal dialysis related peritonitis: a single center retrospective cohort study in Japan

Yamaguchi,

Obayashi,

Kobayashi

et al. 2023

Sci Rep

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We present a single-center retrospective analysis of 228 Japanese patients with peritoneal dialysis, in which we examined whether reduced left ventricular ejection fraction (LVEF) is a risk factor for peritonitis development. Time-dependent multivariable-adjusted Cox proportional hazards models revealed that reduced LVEF (LVEF < 50% vs. preserved LVEF ≥ 50%, hazard ratio (HR) 2.10; 95% confidence interval (CI) 1.16–3.82) was associated with peritonitis. Qualitatively, similar associations with reduced LVEF (< 50%) were observed for enteric peritonitis (adjusted HR 7.68; 95% CI 2.51–23.5) but not for non-enteric peritonitis (adjusted HR 1.15; 95% CI 0.54–2.44). Reduced LVEF is associated with a significantly higher risk of subsequent peritonitis, particularly enteric peritonitis. These results indicate that patients with reduced LVEF may be at risk of enteric peritonitis from bowel sources caused by intestinal involvement due to cardiac dysfunction.

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Section: Discussionsupporting

confidence: 83%