Spontaneous closure of microaneurysms in diabetic retinopathy with treatment of co-existing anaemia

Singh, R; Gupta, Vishali; Gupta, Amod; Bhansali, Anil

doi:10.1136/bjo.2004.050252

Cited by 15 publications

(13 citation statements)

References 4 publications

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“…These results suggested that subjects with low Hb levels tended to have an increased risk of retinopathy, especially that of the severe form. Other studies have corroborated this finding and have also found evidence of improvement in the DR status following correction of anemia [43–45]. Although much attention has been given to anemia in diabetes in recent years, particularly as it relates to kidney disease [46–50], little attention has been given to low Hb levels as a risk factor for the development or worsening of DR. …”

Section: Discussionmentioning

confidence: 78%

Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus

et al. 2012

International Journal of Endocrinology

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Objective. To investigate the risk factors of DR in Chinese T2DM patients. Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the relation between DR and clinical variables. Logistic regression models were used to assess risk for those factors associated with DR. Results. A total of 597 T2DM patients (29.7%) had DR, of which 548 (27.3%) were nonproliferative diabetic retinopathy and 49 (2.4%) were proliferative diabetic retinopathy. Positive correlations were found between DR and duration of diabetes, systolic blood pressure (SBP), diastolic blood pressure, glycated hemoglobin, glycated albumin, 24 hurinary albumin excretion, peripheral atherosclerosis (PA), diabetes nephropathy (DN), diabetic peripheral neuropathy, and anemia. Negative correlations were found between DR and C-peptide and glomerular filtration rate. Logistic regression analysis revealed that duration of diabetes, SBP, DN, anemia, PA, and C-peptide were each independent risk factors of DR. Conclusion. The duration of diabetes, SBP, DN, anemia, and PA are positively associated with DR in Chinese T2DM patients, while C-peptide is negatively associated with DR. Monitoring and evaluation of these related factors will likely contribute to the prevention and treatment of DR.

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Section: Discussionmentioning

confidence: 78%

Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus

et al. 2012

International Journal of Endocrinology

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“…Low hemoglobin has been described as an independent baseline risk factor in the EDTRS for the development of DME and severe visual loss [27]. Other studies have corroborated this finding [18] and have also found improvement in the DME status following correction of anemia [28-30]. Correction of anemia (and also supplementation of erythropoietin) was noted to decrease the effects of retinopathy with structural improvement, possibly through improved oxygenation of the macula [28].…”

Section: Discussionmentioning

confidence: 89%

Association of systemic and ocular risk factors with neurosensory retinal detachment in diabetic macular edema: a case–control study

et al. 2014

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BackgroundDiabetic macular edema (DME) with neurosensory retinal detachment (NSD) remains an important cause of visual loss in patients with diabetes. The aim of the study was to elucidate the association of systemic and ocular risk factors with NSD in DME.MethodsIn a retrospective case–control study, we reviewed clinical records of all the subjects with DME seen between January 2010 and December 2010. Cases and controls were selected based on optical coherence tomography and stereoscopic biomicroscopy review. NSD was defined as subfoveal fluid accumulation under detached retina with or without overlying foveal thickening. The association between the presence of NSD, blood pressure, lipid status and various other biochemical parameters was evaluated.ResultsGroup I (cases) included 37 eyes of 33 patients having DME with NSD and Group II (controls) included 30 eyes of 21 patients having DME without NSD. Patients ranged in age (mean ± SD) from 50 to 62 years (56.6 +/-6.78) for cases and from 51 to 65 years (58.4+/-7.84) for controls. The duration of diabetes ranged from 4 to 15 year (mean 9.45+/-6.08) among cases and 4 to 14 years (9.7+/-5.12) among controls. Significant risk factors for NSD were high values of systolic and diastolic blood pressure (p = 0.039 and 0.043 respectively).ConclusionHigh systolic and diastolic blood pressures are independent and significant risk factors for NSD in DME.

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“…Dennoch bleibt auf lange Sicht die Prognose für den Patienten besser [27]. Entwicklung von Mikroaneurismen und anderen Retinopathien beteiligt ist [38].…”

Section: Hyperglykämieunclassified

Diabetische Retinopathie

2018

Ophthalmologe

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Spontaneous closure of microaneurysms in diabetic retinopathy with treatment of co-existing anaemia

Cited by 15 publications

References 4 publications

Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus

Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus

Association of systemic and ocular risk factors with neurosensory retinal detachment in diabetic macular edema: a case–control study

Diabetische Retinopathie

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