Spontaneous closure of isolated secundum atrial septal defects in infants: An echocardiographic study

Ghisla, Renzo; Hannon, David W.; Meyer, Richard A.; Kaplan, Samuel

doi:10.1016/0002-8703(85)90360-6

Cited by 41 publications

(25 citation statements)

References 11 publications

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“…It is suggested that the presence of an atrial septal tissue flap, originating from anatomic septum primum may be related to the mechanism of closure [13,16]. Spontaneous closure rates of ASDs which were diagnosed under 1 year of age were reported as between 17.2% and 55.0% [14 -16] in some of the studies.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of interatrial septal openings in newborns and predictive factors for spontaneous closure

Ozcelik¹,

Atalay²,

Tutar³

et al. 2006

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

The prevalence of interatrial septal openings in newborns and predictive factors for spontaneous closure

Ozcelik¹,

Atalay²,

Tutar³

et al. 2006

International Journal of Cardiology

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“…Anatomically the ASDs are classified as primum ASD, secundum ASD, sinus venosus ASD, and coronary sinus ASD [4,5,10]. The secundum ASDs are the most common and are located in the region of the fossa ovalis in the atrial septum [1,10].…”

mentioning

confidence: 99%

“…The secundum ASDs are the most common and are located in the region of the fossa ovalis in the atrial septum [1,10].…”

mentioning

confidence: 99%

Spontaneous Closure of Atrial Septal Defects

Helgason

1999

Pediatr Cardiol

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Atrial septal defects (ASDs) are found more frequently in the pediatric population than in adults, and improved diagnostic techniques with echocardiography (2DE) and Doppler facilitate diagnosis so that repair is possible at an optimal time. The purpose of our investigation was to study the size of ASDs at diagnosis, how size changes during follow-up, and to explore the relationship between size at diagnosis and need for surgery. We reviewed the medical records of all patients in Iceland with the diagnosis of ASD born between 1984 and 1993. ASD was confirmed by 2DE in all patients and defects smaller than 4 mm were excluded. ASD size was measured by 2DE from subxyphoid long and short axis views. There were 91 patients-29 males and 62 females. Four patients died from causes other than the heart defect and had not been operated upon. Seven patients with ASD primum and sinus venosus defects were excluded from analysis. There were 29 patients with a 4 mm defect, 17 patients with 5 or 6 mm defects, 8 patients with 7 or 8 mm defects, and 26 patients had defects >8 mm. In the 4 mm group, in 26 patients (89%) the ASD closed spontaneously or decreased in size, and 1 patient had been operated upon. In the 5 or 6 mm group, 15 of 19 ASDs (79%) had closed spontaneously, and 2 patients (9.5%) had been operated upon. In the 7 or 8 mm group, 1 of 6 ASDs (16.6%) had closed spontaneously and 3 had been closed surgically. In the >8 mm group, 1 of 24 ASDs had closed spontaneously and 20 (91%) had been closed surgically. We conclude that defects smaller than 6 mm in diameter are very likely to close spontaneously although follow-up is necessary. Defects larger than 8 mm have a high probability requiring operative closure.

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“…The introduction of echocardiography, Doppler techniques, and color flow mapping has profoundly changed the investigation and management of children with (suspected) heart disease [1,2,5,7,8]. Access to these techniques varies widely around the world, and even within a region indications for their use may differ substantially.…”

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confidence: 99%

High Prevalence of Interatrial Communications During the First Three Months of Life

Hansen

Oxhøj

1997

Pediatr Cardiol

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The objective of this study was to analyze retrospectively the results of color Doppler echocardiographic (CDE) investigations performed for the first time on a child under circumstances where there was unrestricted access to CDE. The records were obtained from a tertiary referral center at a university hospital serving a population of about one million. The patients were children (n = 284) ages 0 days to 15 years 9 months referred for CDE over a 1-year period. Heart abnormalities were found in 119 children (42%). Among the children <3 months old, a heart abnormality was detected by CDE in 71%. The most prevalent diagnosis was atrial septal defect, particularly during the first 3 months of life, where the intraatrial communications accounted for 78% of the heart abnormalities. It is concluded that there is high prevalence of atrial communications during the first 3 months of life. The spectrum of diagnoses among newborns differs from the previously reported frequencies of congenital heart diseases. Better equipment (CDE) seems to diagnose abnormalities that might not be diagnosed otherwise.

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Spontaneous closure of isolated secundum atrial septal defects in infants: An echocardiographic study

Cited by 41 publications

References 11 publications

The prevalence of interatrial septal openings in newborns and predictive factors for spontaneous closure

The prevalence of interatrial septal openings in newborns and predictive factors for spontaneous closure

Spontaneous Closure of Atrial Septal Defects

High Prevalence of Interatrial Communications During the First Three Months of Life

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