Spontaneous Clitoral Hood Epidermal Inclusion Cyst Mimicking Clitoromegaly in a Pediatric Patient

Clitoris cyst mimicking ambiguous genitalia and presenting spontaneous regression

“…5 The spontaneous regression of the cyst in the present case is noteworthy. Although this is described as possible in the literature in epidermoid cysts, 3 we were not able to identify any case of epidermoid cyst of the clitoris with similar evolution in the literature. Thus, we believe that surgical intervention should be indicated with caution in these cases, perhaps considering the child's age, due to the possibility of spontaneous regression of the cyst.…”

“…2 Schober et al identified <10 case reports in their review in 2014. 3 The typical physical finding consists of a soft, movable and non-hardened lump in the clitoral region in the absence of any sign of virilization. 1 When present at birth, they may cause significant clitoromegaly, and be confused with ambiguous genitalia, 3 as occurred in the present case.…”

“…3 The typical physical finding consists of a soft, movable and non-hardened lump in the clitoral region in the absence of any sign of virilization. 1 When present at birth, they may cause significant clitoromegaly, and be confused with ambiguous genitalia, 3 as occurred in the present case. The clitoris enlargement due to hormonal causes or disorders of sexual differentiation differs from epidermoid cysts because it is symmetrical and uniform.…”

Spontaneous nontraumatic epidermoid cyst of the clitoris: a rare case report

“…[2][3][4] Only one case of clitoral epidermoid cyst following accidental trauma has been reported by Neslihan Celik et al 10 There have been only few reported cases of congenital or idiopathic epidermoid cysts of the clitoris without history of female genital mutilation. [11][12][13][14][15][16][17][18] In our case, there was no history of female genital mutilation/trauma, and neither any history of oral contraceptive use or any other drug intake.…”

Clitoromegaly in Childhood and Adolescence: Behind One Clinical Sign, a Clinical Sea

“…Inclusion cysts in the female external genitalia (clitoris, vulva, and even vagina) are a not uncommon complication following circumcision and are well documented in the literature. They are due to traumatic transplantation of the epidermis into intradermal or subcutaneous tissue with subsequent proliferation of epidermal cells [Schober et al, 2014]. Cysts have an outer wall of epidermis and a center filled with keratin material arranged into laminae.…”