1974
DOI: 10.1007/bf00328860
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Spontaneous chromosome rearrangements in an established cell line of Drosophila melanogaster

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1976
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Cited by 14 publications
(3 citation statements)
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“…Finally, it is worth recalling that there is considerable similarity between the chromosomal behaviour described in vivo and that observed in vitro (Halfer, 1978;Faccio Dolfini & Halfer, 1978), even though the chromosomal polymorphism in vitro is expressed more intensely. However, further studies, with application of different cytological techniques, may disclose as yet undetected patterns of variation in the structure of the chromosomes, thus providing new markers for cytogenetic investigations.…”
Section: Discussionmentioning
confidence: 99%
“…Finally, it is worth recalling that there is considerable similarity between the chromosomal behaviour described in vivo and that observed in vitro (Halfer, 1978;Faccio Dolfini & Halfer, 1978), even though the chromosomal polymorphism in vitro is expressed more intensely. However, further studies, with application of different cytological techniques, may disclose as yet undetected patterns of variation in the structure of the chromosomes, thus providing new markers for cytogenetic investigations.…”
Section: Discussionmentioning
confidence: 99%
“…A second indication derived from the fluorescence pattern described first by VosA (1970) and confirmed later by FACCIO DoLFINI (1974). This 4th chromosome is brightly fluorescent, which may mean that a considerable part of it is heterochromatic.…”
mentioning
confidence: 82%
“…In addition, the detailed analysis of karyotypes in the 1182-4 cell line shows a surprising occurrence (up to 0.5%) of aneuploid constitutions with monosomies for the 2nd or the 3rd chromosomes; such monosomies are lethal for the flies. It is unknown if such constitutions are also cell lethal, but they have never been observed in other Drosophila cell lines [27].…”
Section: Historical Perspective: the Origins Of The Acentriolar 1182-4 Drosophila Cell Linementioning
confidence: 99%