Spontaneous candida mediastinitis diagnosed by endoscopic ultrasound-guided, fine-needle aspiration

Abstract

Candida mediastinitis is a rare clinical entity associated with high mortality and morbidity. It is emerging as an important clinical entity, probably due to increased recognition of candida as a significant pathogen in mediastinitis. Candida mediastinitis is usually associated with cardiothoracic surgery, esophageal perforation, and head and neck infections. Optimal therapy for candida mediastinitis remains undefined. Aggressive, combined surgical debridement and antifungal therapy appears to be the most effective of available therapies. We report a case of spontaneous candida mediastinitis diagnosed by endoscopic ultrasound-guided, fine-needle aspiration and successfully treated with oral antifungal therapy alone.

Spontaneous mediastinitis with multiple esophageal abscess in the esophagus

“…Considering that all the results get from the analysis were negative, we could classify this case as a spontaneous mediastinitis. Being the mediastinitis a rare cause of chest pain [ [6] , [7] , [8] ], the spontaneous mediastinitis is even more exceptional, and that is what makes our case significant. Another remarkable fact, is the clinical presentation of this case [ [6] , [7] , [8] ], where the initial symptoms were epigastric pain and dyspnea, which make the diagnosis of this illness ever more complicated.…”

“…Being the mediastinitis a rare cause of chest pain [ [6] , [7] , [8] ], the spontaneous mediastinitis is even more exceptional, and that is what makes our case significant. Another remarkable fact, is the clinical presentation of this case [ [6] , [7] , [8] ], where the initial symptoms were epigastric pain and dyspnea, which make the diagnosis of this illness ever more complicated. Therefore, this diagnosis could be taken into account when other causes of chest pain or epigastric pain were reasonable discarded.…”