Spontaneous abdominal implantation in the rat with development to full term

Gosden, R. G.; Russell, John A.

doi:10.1258/002367781780953022

Cited by 9 publications

(6 citation statements)

References 8 publications

(9 reference statements)

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“…Ectopic pregnancies have also been described in other non-primate laboratory animals such as guinea pigs (Araujo 1964, Hong & Armstrong 1978, rabbits (Smith et al 1989, Arvidsson 1998, Beddow 1999, Owensby et al 2001, hamsters (Buckley & Caine 1979, Peters 1982, rats (Gosden & Russell 1981, Polzenhagen et al 1983, and mice (Bloch 1962, King et al 1978. Abdominal pregnancies were diagnosed in all cases except for a rat (Polzenhagen et al 1983) and a mouse (King et al 1978), where ovarian and tubal pregnancies respectively were proposed.…”

Section: Laboratory Animalsmentioning

confidence: 95%

“…Whereas abdominal pregnancy has been regularly reported to be compatible with full-term development in humans , it is very rare or unknown in domesticated and laboratory species (Gosden & Russell 1981). Only two references have been found of animals with abdominal pregnancy, where a caesarean was performed and the lambs and kittens were alive (Feeney & Johnston 1983, Mitchell 1989.…”

Section: Abdominal Pregnanciesmentioning

confidence: 99%

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Ectopic pregnancy in animals and humans

Corpa¹

2006

Reproduction

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Ectopic pregnancy denotes a pregnancy occurring elsewhere than in the cavity of the uterus. This pathology has been recognised for years and it causes numerous maternal deaths during the first trimester of pregnancy. While this condition is wellknown in humans, it is rarely diagnosed in animals. However, the causes and mechanisms leading to an ectopic implantation of the ovum are not always clearly defined in humans or animals. Two types of ectopic pregnancy are mainly recognized: (1) tubal pregnancy occurs when an oocyte is fertilized and then remains in the oviduct and (2) abdominal pregnancy occurs when the gestation develops in the peritoneal cavity. The latter may be subdivided into two subtypes: the primary form, when a fertilized oocyte enters the peritoneal cavity and becomes attached to the mesentery or abdominal viscera, and the secondary form, which follows the rupture of an oviduct or the uterus after the fetus has been implanted, and the fetus is expelled into the peritoneal cavity. Cornual, ovarian and cervical ectopic locations are less frequent. Several differences exist in ectopic pregnancies between human beings and animal species. While abdominal pregnancy has been described in both human and animal species, tubal ectopic pregnancies would appear to be restricted to primates. Other than anecdotal cases, this pathological condition does not occur in laboratory, domestic or farm animals. Several factors are described as being the cause of these differences.

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Section: Laboratory Animalsmentioning

confidence: 95%

Section: Abdominal Pregnanciesmentioning

confidence: 99%

Ectopic pregnancy in animals and humans

Corpa¹

2006

Reproduction

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“…This anomaly is mainly observed in humans, although it has been described in many species [12,14,19,26,31,32] . In the majority of cases, the blastocyst implants in the oviduct (tubal implantation).…”

Section: Ectopic Pregnanciesmentioning

confidence: 99%

Comparative Implantation and Placentation

Chavatte‐Palmer¹,

Guillomot²

2007

Gynecol Obstet Invest

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In all placental mammals, the establishment of an intimate contact between the embryo and the mother follows a succession of common critical steps whose chronology and timing may considerably vary from species to species. These processes present a great diversity based on the anatomy and the histology of the uterus, the developmental stage of the embryo at the time of implantation, and the endocrine and molecular interactions between the uterine and the embryonic tissues. This paper provides an overview of the general mechanical, endocrinological and cellular aspects involved in implantation in mammals with an emphasis on domestic species.

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“…EP is a well-known life-threatening disease that affects humans and, although less frequently, other mammals [ 6 ]. It has been described in domestic [ 7 , 8 , 9 ], laboratory [ 10 , 11 , 12 , 13 ] and wild animals [ 14 , 15 , 16 ]. Two main EP types are recognized, tubal and abdominal pregnancy, depending on whether the gestation develops in the fallopian tubes or in the abdominal cavity, respectively.…”

Section: Introductionmentioning

confidence: 99%

Ectopic Pregnancy and T-Cell Lymphoma in a Eurasian Red Squirrel (Sciurus vulgaris): Possible Comorbidity and a Comparative Pathology Perspective

Raso,

Galietta,

Eleni

et al. 2024

Animals

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Ectopic pregnancy (EP) is a life-threatening disease that affects humans and other mammals. Tumors causing ruptures of the reproductive tract have been identified as possible predisposing factors in human and veterinary medicine. We here describe a case of concomitant ectopic pregnancy and lymphoma in a Eurasian red squirrel found deceased in Italy and submitted to the public health laboratory Istituto Zooprofilattico Sperimentale del Lazio e della Toscana (IZSLT) for post-mortem examination. A full-term partially mummified ectopic fetus in the abdomen and a large fibrinonecrotic tubal scar adjacent to the right ovary were observed at necropsy. The tubal scar is likely the point of tubal rupture through which the fetus displaced. Histology revealed the presence of neoplastic cells referable to lymphoma infiltrating the ovary, spleen, small intestine, heart and peripancreatic adipose tissue. The lymphoma was further characterized as T-cell-type using immunohistochemistry. We suggest that the lymphoma, by involving the ovary, played a pathogenetic role in the development of a secondary EP by altering the genital tract at the structural and hormonal levels. To the best of our knowledge, this is the first report of concomitant ovarian lymphoma and EP in animals and humans in the literature.

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Spontaneous abdominal implantation in the rat with development to full term

Abstract: A fully-developed rat foetus was recovered from the peritoneal cavity of a rat, where it had formed a vascular connection to the omentum. Primary implantation on the omentum was inferred.

Cited by 9 publications

References 8 publications

Ectopic pregnancy in animals and humans

Ectopic pregnancy in animals and humans

Comparative Implantation and Placentation

Ectopic Pregnancy and T-Cell Lymphoma in a Eurasian Red Squirrel (Sciurus vulgaris): Possible Comorbidity and a Comparative Pathology Perspective

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