Split‐face study of melasma patients treated with non‐ablative fractionated photothermolysis (1540 nm)

Barysch, Marjam J.; Rümmelein, Bettina; Kolm, Isabel; Karpova, Maria B.; Schönewolf, Nicola; Allemann, Inja Bogdan; Dummer, Reinhard

doi:10.1111/j.1468-3083.2011.04086.x

Cited by 18 publications

(14 citation statements)

References 32 publications

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“…An open clinical study on treatment of melasma in 25 Asian patients using fractional 1550 nm laser recommended judicious use of FPT for treating Asian skin because of its limited efficacy . Recently a split face study on 14 female patients with melasma treated with non‐ablative FPT (1540 nm) showed good results in skin types I and II but emphasized its critical evaluation in patients with darker skin complexions . A study analyzing histological and electron microscopic changes after fractional resurfacing suggested that the clinical improvement should not be interpreted as a cure for melasma …”

Section: Discussionmentioning

confidence: 98%

Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients

Shaikh

Mashood

2013

Int J Dermatol

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Section: Discussionmentioning

confidence: 98%

Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients

Shaikh

Mashood

2013

Int J Dermatol

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“…Already after one treatment, improvement has been described for photodamaged skin, skin laxity, facial rhytides and acne scarring. Positive experiences in our own clinical trial using the non-ablative fractionated ErYAG-laser to treat melasma [21] motivated us to perform the present study. However, ablative fractionated CO 2 -laser (Quantel Excel O2) showed only little efficacy in this indication and was clearly less effective than the standard laser treatment with the QS ruby laser (Sinon).…”

Section: Discussionmentioning

confidence: 99%

Laser treatment of solar lentigines on dorsum of hands: QS Ruby laser versus ablative CO2 fractional laser – a randomized controlled trial

Schoenewolf

Hafner

Dummer

et al. 2015

European Journal of Dermatology

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To cite this article: Schoenewolf NL, Hafner J, Dummer R, Bogdan Allemann I. Laser treatment of solar lentigines on dorsum of hands: QS Ruby laser versus ablative CO 2 fractional laser -a randomized controlled trial. Eur J Dermatol 2015; 25(2): 122-6Background: Lentigines solares (LS) on the dorsum of hands are often esthetically disturbing. Q-switched ruby laser treatment is highly effective in the treatment of these lesions. Ablative fractional photothermolysis may be a suitable alternative. We compared the Q-switched ruby laser with ablative CO 2 fractional photothermolysis for the treatment of solar lentigines. Objective: To evaluate the efficacy and side-effects of 694nm Q-switched ruby laser (Sinon) with the ablative 10,600nm CO 2 fractional laser (Quantel Excel O2) in an intra-individual side-to-side comparison in the treatment of LS on the dorsum of hands. Material and methods: Eleven patients were included in the study. The hands of each patient were randomized for treatment with the two laser systems. Three treatment sessions were scheduled at weeks 0, 4 and 8. Evaluations by patients, treating physician and blinded experts were scheduled at weeks 0, 4, 8, 16 and 24. Results: The Q-switched ruby laser was significantly more efficacious than the ablative CO 2 fractional laser for removing LS on the dorsum of hands (p = 0.01). Conclusion: In this first study on this topic, the Q-switched ruby laser was superior to the ablative CO 2 fractional laser in the treatment of lentigines solares on the dorsum of hands.

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“…In addition, 17% of patients suffered from worsening lesions because of PIH (skin types III and IV). The authors noticed that despite its lower side effects, NAFL requires prudence in darker skin types (III+) because of the PIH risk, and sessions should be performed, if any at all, with low densities [24] .…”

Section: Non-ablative Fractionated Lasersmentioning

confidence: 99%

Energy-based devices for treatment of melasma

Jordão

Rebellato

2017

J Surg Dermatol

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Melasma, as a pigmentation disorder, induces significant stress to the patients and its recurrent nature remains a challenge in clinical practice. Treatment is based on a variety of mechanisms to prevent and/or stop the pigment production process by destroying the deposited pigment for removal or release, by peeling cells to improve their turnover, and by reducing inflammation. The use of appropriate devices and correct settings are crucial in the treatment of melasma. Cases unresponsive to topical bleaches or chemical peels should be referred for laser therapy. It is important that a maintenance therapy to avoid the recurrence of melasma be indicated. In this paper, we review energy-based devices for melasma treatment.

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Split‐face study of melasma patients treated with non‐ablative fractionated photothermolysis (1540 nm)

Cited by 18 publications

References 32 publications

Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients

Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients

Laser treatment of solar lentigines on dorsum of hands: QS Ruby laser versus ablative CO2 fractional laser – a randomized controlled trial

Energy-based devices for treatment of melasma

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