Splenosis of the Mesoappendix with Acute Appendicitis: A Case Report

Abstract

Rare co-existance of disease or pathology Background:Splenosis is a benign condition involving the auto-transplantation of splenic tissue at various locations, resulting from splenic injury or splenectomy. Case Report:A 40-year-old male, with a history of remote exploratory laparotomy with splenectomy secondary to blunt abdominal trauma, presented with symptoms consistent with acute appendicitis, which was subsequently confirmed by computed tomography scan of the abdomen that further demonstrated the presence of multiple abdominal nodules, one of which was adjacent to the appendix. A laparoscopic appendectomy was then performed along with resection of the nodule located in the mesoappendix, which was confirmed to be a splenic tissue based on histopathological examination. Conclusions:Abdominal splenosis is not an uncommon condition in patients with a history of splenic injury. However, the involvement of the mesoappendix, which may or may not contribute to acute inflammation of the appendix, is very rare.

Pelvic mass causing hematospermia: splenosis

“…Splenosis was first reported by Albrecht [ 9 ] in 1896, and Buchbinder and Lipkoff [ 10 ] named this disease in 1939. Splenosis occurs in 26%-67% of patients with a history of splenic rupture and splenectomy [ 4 , 5 , 11 , 12 ]. In general, splenosis grows slowly and rarely causes invasion.…”

“…Patients usually have no discomfort symptoms, and it is often accidentally found in physical examination, imaging examination, abdominal surgery and other cases [ 2 , 4 ]. Spleen tissue or cells can be transplanted not only in various parts of the abdominal cavity [ 4 , 6 , 8 , 13 – 15 ], but also in the retroperitoneal cavity, the chest and even the brain [ 1 , 3 , 6 , 16 – 18 ]. There have been reported cases of spleen transplantation in the kidney and adrenal gland [ 17 , 18 ].…”

“…Splenosis occurs after rupture of the spleen or splenectomy [8], and its essence is heterotopic autologous splenic tissue implantation [2][3][4]. Splenosis was first reported by Albrecht [9] in 1896, and Buchbinder and Lipkoff [10] named this disease in 1939.…”

“…Due to limited blood supply, most implanted spleens are nodular and smaller than 3 cm in diameter, often do not need surgical intervention. However, in a small number of patients, the implanted spleen showed tumor-like growth with a diameter of up to 10 cm [ 4 , 5 ]. Surgical treatment is usually required when a large implant or a specific implant site causes nonspecific abdominal pain, hydronephrosis, gastrointestinal bleeding, or intestinal obstruction [ 3 , 6 ].…”

Splenosis: fetters of the unknown or step through existing precautions (part I)

“…Помимо посттравматического генеза спленоз может иметь ятрогенный характер в случае целенаправленной аутотрансплантации ткани селезенки при необходимости удаления данного анатомического образования, проводящейся с целью профилактики постспленэктомического синдрома. Как правило, регенераторные очаги селезеночной ткани локализуются на париетальной и висцеральной брюшине, в ложе удаленной селезенки, но могут обнаруживаться во всем теле (даже в головном мозге), в различном количестве и разнообразных размеров [1][2][3][4][5].…”