Splenosis: fetters of the unknown or step through existing precautions (part I)

Abstract

Aim: to present a rare clinical case of multiple post-traumatic intra-abdominal splenosis in combination with type 2 macroamylasemia, chronic pancreatitis in a 27-year-old woman, clinically manifested like a palpable mass in the right iliac region.Main results. In the first part of the article, a detailed analysis of the medical history is given, the results of archival imaging studies and the data of laboratory and instrumental examination at the time of treatment are presented. The literature review presents modern definitions of splenosis, as well as brief information about the anatomy and physiology of the spleen.Conclusion. The diagnostic process requires a detailed analysis of the history of the disease, the performance of laboratory studies in combination with modern imaging studies, as well as a thorough study of the literature data.

A very rare case of splenosis and acquired chronic non‐cirrhotic portal vein thrombosis with cavernous transformation

“…Acute PVT includes abdominal pain, fever, nausea, vomiting, and ascites; episodes of gastrointestinal bleeding are often observed in patients with the background of chronic PVT. 6 According to some studies, PVT can also be asymptomatic. It is diagnosed when there are complications such as varicose bleeding.…”

“…Despite the relatively acceptable vascularization, the total amount of filtered blood is sharply reduced. The microanatomy of the regenerative nodes of the spleen is probably unable to provide close contact between the antigen, phagocytes, and immune cells that are characteristic of a normal spleen 6 …”

“…The microanatomy of the regenerative nodes of the spleen is probably unable to provide close contact between the antigen, phagocytes, and immune cells that are characteristic of a normal spleen. 6 The recurrence of hematological symptoms in patients who have undergone splenectomy indicates the presence of splenosis. 2,4 The hematological symptoms in our patient resumed at the age of 20 years, 13 years after the procedure.…”