Splenic littoral cell angioma in an infant

Antón-Pacheo, J.; Ayuso, Rosa María Fernández; Cano, Irene; Martínez, M. Almenara; Cuadros, J.; Berchi, F. J.

doi:10.1016/s0022-3468(00)90225-2

Cited by 19 publications

(10 citation statements)

References 7 publications

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“…1, 4 -8 Before this report, the youngest reported patient diagnosed with LCA was 1 year of age. 4 Approximately 30% of cases are diagnosed incidentally. The remaining patients present with nonspecific signs or symptoms such as fever, abdominal pain, splenomegaly, or thrombocytopenia.…”

Section: Discussionmentioning

confidence: 99%

A Novel Presentation of Littoral Cell Angioma and Lymphatic Malformations in a Neonate

et al. 2018

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This case report describes a novel presentation of littoral cell angioma (LCA) and lymphatic malformations involving the omentum and mesentery. To our knowledge, these 2 entities have not been reported in the same patient. A 1-month term infant male presented with chylous ascites. During his workup, imaging detected splenic nodules. Biopsies revealed that the nodules were LCA and the chylous ascites was secondary to microscopic mesenteric and omental lymphatic malformations. Evaluation for a secondary malignancy, an underlying immunologic defect, and genetic causes were unrevealing. The presence of LCA and lymphatic malformations in the same patient suggests a genetic link between these 2 rare vascular disorders and may help elucidate the etiopathogenesis of these 2 poorly understood anomalies.

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Section: Discussionmentioning

confidence: 99%

A Novel Presentation of Littoral Cell Angioma and Lymphatic Malformations in a Neonate

et al. 2018

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“…Only a handful of pediatric cases have been reported thus far. [ 1 3 4 5 ] LCA is usually asymptomatic and is only discovered incidentally. Clinically, LCA may be characterized as a solid mass occurring most often along with splenomegaly, thrombocytopenia, or anemia, as well as a fever of unknown origin.…”

Section: Discussionmentioning

confidence: 99%

Littoral cell angioma: A rare cause of pediatric thrombocytopenia

Jasani¹,

Shah²

2018

J Indian Assoc Pediatr Surg

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“…Our case had these immunohistochemical findings including the focal S100 positivity. The differential diagnosis of LCA includes other vascular tumors of the spleen, namely splenic hemangioma, cystic lymphangioma, angiosarcoma and vascular hamartoma as well as peliosis [5]. Morphologic and immunophenotypic features allow one to distinguish LCA from other vascular tumors [3,5].…”

Section: Discussionmentioning

confidence: 99%

“…Although splenic hemangiomas appear similar to hemangiomas of other anatomical sites, littoral cell angioma (LCA) is unique to this organ. LCA derives from the littoral cells lining the splenic red pulp sinuses [2][3][4][5]. Its morphologic and immunologic features are different from the features of the cavernous and capillary hemangiomas [2].…”

Section: Introductionmentioning

confidence: 99%

Littoral cell angioma: A case report

Özkök¹,

Taşlı²,

Keçeci³

et al. 2014

MMJ

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We report the case of a 43-year-old male with a littoral cell angioma. Clinical examination of the spleen revealed multiple cystic masses surrounded by normal splenic tissue. Histopathologic and immunohistochemical findings confirmed the diagnosis of a littoral cell angioma. The rarity in the literature of littoral cell angiomas is striking.Key words: Littoral cell angioma, Spleen, Vascular tumor ÖZET Bu yazıda splenektomi materyelinde littoral hücreli anjiom tanısı olan 43 yaşında bir erkek hasta sunulmuştur. Hastanın klinik incelemesinde dalakta çok sayıda kistik kitleden oluşan lezyon saptanmıştır. Histopatolojik ve immunohistokimyasal bulgular littoral hücreli anjiom tanısını desteklemiştir. Lezyon son derece nadir olması nedeni ile tartışmaya değer bulunmuştur.

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Splenic littoral cell angioma in an infant

Cited by 19 publications

References 7 publications

A Novel Presentation of Littoral Cell Angioma and Lymphatic Malformations in a Neonate

A Novel Presentation of Littoral Cell Angioma and Lymphatic Malformations in a Neonate

Littoral cell angioma: A rare cause of pediatric thrombocytopenia

Littoral cell angioma: A case report

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