Splenic HIV infection diagnosed with p24 on autopsy cytopathology confirmed on histopathology

Cell blocks are not a substitute for cytology: why pathologists should understand cytopathology particularly in their chosen speciality

“…11 Neuropathologists for many years have favoured imprint cytology over frozen sections of friable brain material; 12 and autopsy diagnosis can be augmented by imprint cytology, which may avoid the need to save tissue samples. 13 Imprint cytology preceded histology historically, 14 and may precede histology in practice sometimes making biopsy or resection unnecessary.…”

Haematocytopathology: why?

“…Moreover, many non‐lymphomatous reactive, immunodeficiency‐related and lymphomatous processes may involve non‐haematological organs or be closely intermingled with them but require haematological tools and knowledge to be managed. A proof of these connections is reported in this issue of Cytopathology : three articles 1–3 describe the cytological features of lymphoproliferative disorders associated with Castleman’s disease, Kaposi sarcoma‐associated herpes virus, HIV and Epstein–Barr virus.…”

“…The articles by Önder et al. 16 and the letter by Lucas 3 exploit the application of splenic cytology in the diagnosis of a rare entity in one, and an unsuspected HIV infection in the other. These two articles re‐assert the contribution that cytology, since the dawn of clinical cytology 17 up to more recent experiences, 18,19 can offer in the diagnosis of all types of splenic pathology.…”