Splenic diffuse large B-cell lymphoma. Case report

Abstract

Lymphomas are defined as a solid tumor of the lymphoid tissue, of malignant biological behavior, and with great diversity of clinical and histological forms. It originates in lymph nodes in 35% of cases or in the lymphoid tissue of the parenchyma of the original organ in 65% of cases. Lymphomas are classified into two major groups: Hodgkin's disease and non-Hodgkin's lymphomas (NHL). The spleen may be involved in a wide variety of lymphomas; in some cases they infiltrated said organ as part of a broad diffusion of a base node other particular lymphoma. Splenectomy with liver biopsy and biopsy of the para-aortic lymph node is the treatment of choice for splenic lymphoma. In patients with low-grade NHL confined to the spleen, complete remission of the associated haematological abnormality may reach approximately seven months after splenectomy. Postoperative adjuvant therapy depends on the clinical stage of the disease.