Spindle Cell Lipoma: A Case Report And Review Of Literature

Abstract

Oral spindle cell lipoma is a rare lesion and until now only 26 cases have been reported in English literature. In this article we report a case of oral spindle cell lipoma presented to our institution in July 2011, as an asymptomatic solitary growth of the buccal mucosa in a 58 year old male patient. On histopathological examination the lesion exhibited an admixture of adipocytes and spindle cells with collagen fibres and numerous mast cells. Kathmandu University Medical Journal | Vol.10 | No. 2 | Issue 38 | Apr – June 2012 | Page 92-95 DOI: http://dx.doi.org/10.3126/kumj.v10i2.7353

Spindle cell lipoma

“…Mitosis, cellular pleomorphism and nuclear hyperchromasia are extremely rare or absent 6. The histopathological features of the present case fulfilled the above description.…”

“…Fibrolipomas are less cellular than SCLs and show large bundles of collagen. Pleomorphic lipomas are marked by the presence of large multinucleated floret-type giant cells with multiple radially arranged nuclei 6. Distinct histopathological features with positive immunostaining of spindle cells with S-100 protein helps in identifying nerve tumours and lipomatous neurofibroma 13…”

Spindle Cell Lipoma of the Soft Palate

“…Lipomas are benign tumours that develop via the proliferation of adipocytes [ 9 ]. There are various theories of the origin of lipomas, including heredity, a hormonal aetiology, infection, metaphase of muscle cells, the presence of lipoblastic embryonic cells, and chronic irritation [ 10 ]. Some reports suggest that 13q locus deletions and altered 8q11–13 cause lipomas [ 11 ].…”

“…Lipomas of the oral cavity are rare and comprise 0.5% of all oral cavity tumours [ 2 ]. Lipomas of the oral cavity form a slow-growing mass with a smooth surface [ 10 ]. SCLs were first described in 1975 by Enzinger and Harvey [ 12 ].…”

Spindle cell lipoma of the mandibular mucogingival junction: a case report of unusual oral neoplasm

“…8 In contrast, localization of SCL to the oral cavity is extremely rare, and few case reports and small case series have been reported in the English literature. 4,9,10,11 In these cases, SCL has presented as a well-circumscribed mass that affects different anatomical locations within the oral cavity, including the buccal mucosa, tongue, floor of the mouth, hard palate and gingiva. 5,11,12 Furthermore, there have been only two case reports of SCL in the gingiva and alveolar ridge mucosa.…”