Spindle cell lipoma

Pardhe, Nilesh; Singh, Neeraj; Bharadwaj, Gaurav; Nayak, Prathibha Anand

doi:10.1136/bcr-2013-010438

Cited by 7 publications

(7 citation statements)

References 12 publications

(12 reference statements)

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“…Another feature of note is the mast cells which are a feature in almost all SCLs [8, 19], also revealed in the histological findings of this case.…”

Section: Discussionsupporting

confidence: 65%

“…First, the lesion is composed of bland mitotically inactive spindle cells arranged in parallel registers between the fat cells, associated with thick rope-like collage bundles [7]. The other is the immunohistochemical stains for CD34 highlighting the bland spindle cell [6] and negative staining with S-100 protein [6, 8]. This was demonstrated in this case.…”

Section: Discussionmentioning

confidence: 81%

“…This gender predilection may be partly explained by androgen receptor's reactivity [8]; however, the exact mechanism is still unknown [17]. …”

Section: Discussionmentioning

confidence: 99%

“…SCLs are typically seen in the neck, trunk, and shoulder region in elderly males [6–8] in the fifth to seventh decade [9]. They are slow-growing, benign mesenchymal neoplasms, composed of mature adipocytes, usually surrounded by a thin fibrous capsule.…”

Section: Introductionmentioning

confidence: 99%

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Rare Occurrence of Lip Spindle Cell Lipoma

Girgis

Cheng

2015

Case Reports in Oncological Medicine

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Spindle cell lipoma (SCL) is a rare distinct variant of lipoma, which presents as a painless, circumscribed, slow-growing, superficial lesion on the lip and can mimic a minor salivary gland tumour. We present a slow growing lower lip lesion and its management. Case Report. A 38-year-old female gave an eight-year history of a slow-growing mass on her lower lip with intermittent change in size. She presented with a submucosal nodule and thin overlying mucosa adjacent to the vermilion border. Surgical excision was carried as the diagnostic and therapeutic approach. Conclusion. Lip SCL is rare, and surgical excision is advocated in order to exclude underlying pathology and minor salivary gland tumours.

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“…Another feature of note is the mast cells which are a feature in almost all SCLs [8, 19], also revealed in the histological findings of this case.…”

Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 81%

“…This gender predilection may be partly explained by androgen receptor's reactivity [8]; however, the exact mechanism is still unknown [17]. …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Rare Occurrence of Lip Spindle Cell Lipoma

Girgis

Cheng

2015

Case Reports in Oncological Medicine

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“…[ 10 ] Immunocytochemical studies with CD34, bcl-2, 21, 24 assists in differentiating lipomas from other myxoid lesions. [ 18 ] However, immunohistochemistry was not done in our patient due to financial constraints and the histopathological diagnosis was definite and in accordance with clinical findings.…”

Section: Discussionmentioning

confidence: 63%

A rare presentation of lipoma on mandibular mucogingival junction

Sharma¹,

Jain²,

Nagpal³

et al. 2016

J Indian Soc Periodontol

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Lipoma is the most common tumor of mesenchymal tissues of body, but its occurrence in oral cavity is infrequent. Buccal mucosa is the most common intraoral site of lipoma followed by tongue, floor of the mouth, and buccal vestibule. The involvement of mucogingival junction is rare. We present a unique case report of oral lipoma occurring on mandibular mucogingival junction with review of literature which has emphasis on differential diagnosis.

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Unusual lipid poor spindle cell lipoma

Schwartz

Subhawong

et al. 2023

BMJ Case Rep

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Spindle cell lipomas (SCLs) containing minimal fat are rare and can be diagnostically challenging due to their similar radiographic appearance to other benign and malignant tumours. SCLs are benign lipomatous tumours that typically occur in middle aged to elderly men as slow-growing, painless masses in the subcutaneous tissue of the posterior neck, shoulders or back. However, rarely these tumours can arise in unusual locations such as the lower extremities. We present an unusual case of a lipid poor SCL occurring in the lower extremity. Initial clinical and radiographic findings were suspicious for a malignancy. Two core biopsies demonstrated benign fibro collagenous tissue, so a marginal excision was performed. Final histopathological and immunohistochemical stains confirmed the diagnosis of an SCL. Radiologists, pathologists and oncologic surgeons should be aware of this lipomatous tumour’s potential to present in unusual locations with minimal fatty components to increase confidence in radiologic-pathological concordance.

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Spindle cell lipoma

Cited by 7 publications

References 12 publications

Rare Occurrence of Lip Spindle Cell Lipoma

Rare Occurrence of Lip Spindle Cell Lipoma

A rare presentation of lipoma on mandibular mucogingival junction

Unusual lipid poor spindle cell lipoma

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