Spinal nerve root compression

Olmarker, Kjell

doi:10.3109/17453679109153920

Cited by 68 publications

(2 citation statements)

References 60 publications

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“…That nerve root volume correlated with CSF volume in our study suggests that factors influencing CSF volume, such as BMI, might similarly influence nerve root volume. The cauda equina nerve roots consist of axons and loose connective tissue enclosed in a thin sheath [14]. Pressure transmitted through the CSF from compression of the dural sac might compress this connective tissue, decreasing the size of the nerve roots.…”

Section: Discussionmentioning

confidence: 99%

The correlation between cauda equina nerve root volume and sensory block height after spinal anaesthesia with glucose-free bupivacaine

Martyr¹,

Song²,

Hua³

et al. 2011

Anaesthesia

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SummaryWe examined the association between cauda equina nerve root volume and sensory block height in 15 patients undergoing spinal anaesthesia with 0.5% glucose-free bupivacaine. Magnetic resonance imaging and a separate image segmentation program were used to calculate the volume of the nerve roots. Nerve root volume was also correlated with lumbosacral cerebrospinal fluid volume and with patients' physical characteristics. Nerve root volume correlated negatively with sensory block height (Spearman rho )0.61 (95% CI )0.85 to )0.14)) and body mass index (Spearman rho )0.66 (95% CI )0.87 to )0.24)) but positively with cerebrospinal fluid volume (Spearman rho 0.76 (95% CI 0.43-0.91)). Factors that are thought to influence cerebrospinal fluid volume, such as body mass index, might similarly affect the volume of the nerve roots. The size of the nerve roots may influence the spread of spinal anaesthesia.

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Section: Discussionmentioning

confidence: 99%

The correlation between cauda equina nerve root volume and sensory block height after spinal anaesthesia with glucose-free bupivacaine

Martyr¹,

Song²,

Hua³

et al. 2011

Anaesthesia

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“…Experiments suggest that low pressure compression of the cauda equina at two sites may be important, but the role of exercise which evokes symptoms is unexplained. Using an approach adopted by Olmarker (1991) and Olmarker et al (1992), we have used an animal model to examine factors which affect cauda equina blood flow during compression and contractions of the tail muscles.…”

Section: University Of Aberdeen Aberdeen Ab9 1asmentioning

confidence: 99%

Demonstrations

1994

The Journal of Physiology

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DEMONSTRATIONSData analysis and information processing in biomedical sciences: a second year module in the degree of Biomedical Sciences at the University of Aberdeen F. Bowser-Riley, K.R. Page and M.A. Radcliffe Department of Biomedical Sciences, Marischal College, University of Aberdeen, Aberdeen AB9 lASThe objective of this course (12 weeks, one-third full time) is to provide junior undergraduate students with a knowledge base concerning methods of information retrieval, data processing and presentation of scientific material. This is achieved in conjunction with the development of teamwork, communication and information technology skills.The course consists of lectures, tutorials, group discussions, directed microcomputer working sessions and preparation by each student of a 3500 word project essay selected within an area of the Biomedical Sciences not encountered previously. The essay is submitted in electronic format and a summary of it is presented orally using electronic media.Initially the students are provided with a grounding in microcomputer applications using MS-DOS, spreadsheet, word processing and graphics software (supported by course booklets). The skills involved in the analysis and presentation of scientific information are developed through worksheets based upon spreadsheet exercises involving experimental data drawn from physiological and anatomical examples. Instruction is given in the use of library resources (including IT-based bibliographic techniques) and in the presentation of scientific papers and oral communications. The skills are applied collectively in the context of the project essay. The topics are researched in the literature, progress being reviewed by individuals regularly within tutorials and designated peer support groups. Topic summaries are given orally using presentational graphics submitted on disk by a common deadline. Finally, the illustrated essays are submitted in word processed format. Marks are awarded to individuals by continuous assessment, a component of which is derived from a peer assessment of the oral presentation based on agreed criteria.The demonstration will display the courseware and consider the design, implementation and evaluation of the course.

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Double‐level cauda equina compression: An experimental study with continuous monitoring of intraneural blood flow in the porcine cauda equina

Takahashi

Olmarker

Holm

et al. 1993

Journal Orthopaedic Research

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Compression of the spinal nerve roots may occur clinically at multiple levels at the same time; however, the basic pathophysiology of multi-level compression is largely unknown. In this study, the intraneural blood flow was analyzed continuously in the uncompressed segment between two compression balloons, with a pig used as an experimental model and a thermal diffusion method. At 10 mm Hg compression, there was a 64% reduction of total blood flow in the uncompressed segment compared with pre-compression values. Total ischemia occurred at pressures 10-20 mm Hg below the mean arterial blood pressure. After two-level compression at 200 mm Hg for 10 min, there was a gradual recovery of the intraneural blood flow towards the baseline. Recovery was less rapid and less complete after 2 h of compression. Double-level compression of the cauda equina can thus induce impairment of blood flow, not only at the compression sites, but also in the intermediate nerve segments located between two compression sites, even at very low pressures. These findings may have clinical importance in the understanding of the pathophysiology of multiple-level cauda equina compression.

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Spinal nerve root compression

Cited by 68 publications

References 60 publications

The correlation between cauda equina nerve root volume and sensory block height after spinal anaesthesia with glucose-free bupivacaine

The correlation between cauda equina nerve root volume and sensory block height after spinal anaesthesia with glucose-free bupivacaine

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Double‐level cauda equina compression: An experimental study with continuous monitoring of intraneural blood flow in the porcine cauda equina

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