2023
DOI: 10.1039/d3fd00034f
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Spiers Memorial Lecture: Shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation

Abstract: We have evaluated chimeric streptavidin superoxide dismutase C as a scaffold for an asymmetric transfer hydrogenase, incorporating [Cp*Ir(biot-p-L)Cl] as a cofactor.

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“…The first-generation of ILs, which replace the volatile organic solvents have low vapor pressure, melting point, and broader mobility [49,50]. These hydrolyzable ILs possess dialkylimidazoles and alkyl pyridines as cations, and halides as anions, thus exhibiting aquatic eco-toxicity [51,52]. The second-generation ILs, which are more tunable and stable in water and air contain more biocompatible cations, such as alkyl pyridines, ammonium, and phosphorus, and as anions, hexafluorophosphate and tetrafluoroborate [51].…”
Section: Alternative Modifications Using Ionic Liquidsmentioning
confidence: 99%
“…The first-generation of ILs, which replace the volatile organic solvents have low vapor pressure, melting point, and broader mobility [49,50]. These hydrolyzable ILs possess dialkylimidazoles and alkyl pyridines as cations, and halides as anions, thus exhibiting aquatic eco-toxicity [51,52]. The second-generation ILs, which are more tunable and stable in water and air contain more biocompatible cations, such as alkyl pyridines, ammonium, and phosphorus, and as anions, hexafluorophosphate and tetrafluoroborate [51].…”
Section: Alternative Modifications Using Ionic Liquidsmentioning
confidence: 99%