Sphingolipidoses

Friede, Reinhard L.

doi:10.1007/978-3-642-73697-1_34

Developmental Neuropathology 1989

DOI: 10.1007/978-3-642-73697-1_34

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Sphingolipidoses

Reinhard L. Friede

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“…MRI of the brain demonstrated bilateral perisylvian polymicrogyria (Figure, A–C). BPP is a cortical development malformation 1 characterized by widened Sylvian fissures with an increased number of abnormally small gyri and shallow sulci. Patients present with dysarthria and refractory seizures.…”

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Teaching NeuroImage: Drug Refractory Epilepsy With Developmental Dysarthria Due to Bilateral Perisylvian Polymicrogyria

et al. 2022

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The seizure semiology was described as numbness of the left half of the body followed by tonic posturing and head version to left with loss of awareness lasting for 30 seconds. Additional symptoms included cognitive impairment with delayed and dysarthric speech. Neuropsychological assessment revealed impaired intellectual and cognitive ability. MRI of the brain demonstrated bilateral perisylvian polymicrogyria (Figure , A-C). BPP is a cortical development malformation 1 characterized by widened Sylvian fissures with an increased number of abnormally small gyri and shallow sulci. Patients present with dysarthria and refractory seizures. 2 Study FundingPublication History

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Teaching NeuroImage: Drug Refractory Epilepsy With Developmental Dysarthria Due to Bilateral Perisylvian Polymicrogyria

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Epileptic and imaging findings in perinatal hypoxic-ischemic encephalopathy with ulegyria

et al. 2003

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Sphingolipidoses

Cited by 2 publications

References 122 publications

Teaching NeuroImage: Drug Refractory Epilepsy With Developmental Dysarthria Due to Bilateral Perisylvian Polymicrogyria

Teaching NeuroImage: Drug Refractory Epilepsy With Developmental Dysarthria Due to Bilateral Perisylvian Polymicrogyria

Epileptic and imaging findings in perinatal hypoxic-ischemic encephalopathy with ulegyria

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