Teaching NeuroImage: Drug Refractory Epilepsy With Developmental Dysarthria Due to Bilateral Perisylvian Polymicrogyria

Abstract

The seizure semiology was described as numbness of the left half of the body followed by tonic posturing and head version to left with loss of awareness lasting for 30 seconds. Additional symptoms included cognitive impairment with delayed and dysarthric speech. Neuropsychological assessment revealed impaired intellectual and cognitive ability. MRI of the brain demonstrated bilateral perisylvian polymicrogyria (Figure , A-C). BPP is a cortical development malformation 1 characterized by widened Sylvian fissures with an increased number of abnormally small gyri and shallow sulci. Patients present with dysarthria and refractory seizures. 2 Study FundingPublication History