Sphenopalatine Ganglion Block for the Treatment of Postdural Puncture Headache: A Randomized, Blinded, Clinical Trial

Jespersen, Mads Seit; Jæger, Pia; Ægidius, Karen; Fabritius, Maria Louise; Duch, Patricia; Rye, Ida; Afshari, Arash; Meyhoff, Christian S.

doi:10.1097/01.aoa.0000732464.04840.b5

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A variety of SPGB-techniques have been described, including nasal application via saturated cotton tips, injection or spraying of local anesthetics [ 48 ]. Most recently, intranasal lidocaine nebulization (30–60 mg per nostril) using a mucosal atomization device (MAD) was shown to rapidly reduce pain intensity in obstetrics with PDPH following neuraxial analgesia (both SpA and EDA) and to prevent a later EBP treatment [ 49 ▪ ].…”

Section: Therapeutic Managementmentioning

confidence: 99%

Efficacy of therapies for post dural puncture headache

Thon,

Weigand,

Kranke

et al. 2024

Current Opinion in Anaesthesiology

View full text Add to dashboard Cite

Purpose of review Clinical management of postdural puncture headache (PDPH) remains an interdisciplinary challenge with significant impact on both morbidity and quality of life. This review aims to give an overview of the most recent literature on prophylactic and therapeutic measures and to discuss novel findings with regard to currently published consensus practice guideline recommendations. Recent findings Although current evidence does not support a recommendation of any specific prophylactic measure, new data is available on the use of intrathecal catheters to prevent PDPH and/or to avoid invasive procedures. In case of disabling or refractory symptoms despite conservative treatments, the epidural blood patch (EBP) remains the therapeutic gold standard and its use should not be delayed in the absence of contraindications. However, recent clinical studies and meta-analyses provide additional findings on the therapeutic use of local anesthetics as potential noninvasive alternatives for early symptom control. Summary There is continuing research focusing on both prophylactic and therapeutic measures offering promising data on potential alternatives to invasive procedures, although there is currently no treatment option that comes close to the effectiveness of an EBP. A better understanding of PDPH pathophysiology is not only necessary to identify new therapeutic targets, but also to recognize patients who benefit most from current treatments, as this might enhance their therapeutic efficacy.

show abstract

Section: Therapeutic Managementmentioning

confidence: 99%

Efficacy of therapies for post dural puncture headache

Thon,

Weigand,

Kranke

et al. 2024

Current Opinion in Anaesthesiology

View full text Add to dashboard Cite

show abstract

“…All patients received an SPG block with transnasally inserted hollow cotton swabs. 15 The patients were instructed to lie in a supine position with their neck extended and their nostrils pointed in an upward direction (Fig. 1).…”

Section: Interventionmentioning

confidence: 99%

Sphenopalatine ganglion block for the treatment of postdural puncture headache: a randomised, blinded, clinical trial

Jespersen

Jæger

Ægidius

et al. 2020

British Journal of Anaesthesia

View full text Add to dashboard Cite

Background: Current treatment of postdural puncture headache includes epidural blood patch (EBP), which is invasive and may result in rare but severe complications. Sphenopalatine ganglion block is suggested as a simple, minimally invasive treatment for postdural puncture headache. We aimed to investigate the analgesic effect of a transnasal sphenopalatine ganglion block with local anaesthetic vs saline. Methods: We conducted a blinded, randomised clinical trial including adults fulfilling the criteria for EBP. Participants received a sphenopalatine ganglion block bilaterally with 1 ml of either local anaesthetic (lidocaine 4% and ropivacaine 0.5%) or placebo (saline). Primary outcome was pain in upright position 30 min post-block, measured on a 0e100 mm VAS. Results: We randomised 40 patients with an upright median pain intensity of 74 and 84 mm in the local anaesthetic and placebo groups at baseline, respectively. At 30 min after sphenopalatine ganglion block, the median pain intensity in upright position was 26 mm in the local anaesthetic group vs 37 mm in the placebo group (estimated median difference: 5 mm; 95% confidence interval: e14 to 21; P¼0.53). In the local anaesthetic group, 50% required an EBP compared with 45% in the placebo group (P¼0.76). Conclusions: Administration of a sphenopalatine ganglion block with local anaesthetic had no statistically significant effect on pain intensity after 30 min compared with placebo. However, pain was reduced and EBP was avoided in half the patients of both groups, which suggests a major effect not necessarily attributable to local anaesthetics. Clinical trial registration: NCT03652714.

show abstract

Pattern of Post Dural Puncture Headache Amongst Non Obstetric Surgical Patients in Jlnmch, Bhagalpur, Bihar

Ranjan

Prasad

2022

ijsr

View full text Add to dashboard Cite

The entire research dened the postural puncture headache within the non-obstetric patients in Bhagalpur through the epidemiological survey. It implies the basic problems and issues that can mention the probable chances to implement epidural catheter to reduce the chances of premature rupture. It includes the basic compositions of the medicine and the way it affects the patients as per the gender segregation. Study also implies the effect through time and duration of the pain and hypertensive nature of the pain with inclination of high blood pressure. Study includes proper justication and rationale to highlight the necessity of managing the issues and factors and the way it evaluates accurately.

show abstract

Sphenopalatine Ganglion Block for the Treatment of Postdural Puncture Headache: A Randomized, Blinded, Clinical Trial

Cited by 3 publications

References 0 publications

Efficacy of therapies for post dural puncture headache

Efficacy of therapies for post dural puncture headache

Sphenopalatine ganglion block for the treatment of postdural puncture headache: a randomised, blinded, clinical trial

Pattern of Post Dural Puncture Headache Amongst Non Obstetric Surgical Patients in Jlnmch, Bhagalpur, Bihar

Contact Info

Product

Resources

About