Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol

Pankajakshy, Anitha; Indira, M.

doi:10.1016/j.fertnstert.2008.05.075

Cited by 11 publications

(9 citation statements)

References 7 publications

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“…The extract caused a decrease in all the sperm parameters studied in a dose dependent manner (Table 2). Similar observations suggestive of impaired spermatogenesis were made following oral administration of benzene extract of Carica papaya seeds (Lohiya et al, 1994), ethanolic extract of Canaga odorata root bark (Pankajakshy and Madambath, 2009) and ethanolic extract of Citrulus colocynthis fruit (Chaturvedi et al, 2003).…”

Section: Discussionsupporting

confidence: 68%

Antispermatogenic effects of aqueous ethanolic extract of Hymenocardia acida stem bark in Wistar rats

Abu¹,

Uchendu²

2010

J. Med. Plants Res.

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Oral administration of aqueous ethanolic extract of Hymenocardia acida stem bark for eight weeks caused a significant reduction (P < 0.05) in the weights of testes, epididymides, ventral prostrate, seminal vesicles and vasa differentia compared to the control. The treatment related decreases in sperm motility, count, viability and serum testosterone returned to near normal levels on withdrawal of the extract. The groups that received doses of 100, 200 and 400 mg/kg body weight of the extract showed 40, 0 and 0% fertility, respectively. H. acida stem bark extract adversely affected spermatogenesis in Wistar rats.

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Section: Discussionsupporting

confidence: 68%

Antispermatogenic effects of aqueous ethanolic extract of Hymenocardia acida stem bark in Wistar rats

Abu¹,

Uchendu²

2010

J. Med. Plants Res.

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“…Chlorine is not found oin the cocoon that was feeding with Cananga odorata but in reply the element of Calcium (Ca) is present around 14.37 wt%. The presence of calcium in the cocoon feed with Cananga odorata will give good result in biocompatibility since calcium is essential for cell physiology [12]. The other elements were found the same that are carbon (C), oxigent (O), and kalium (K) as can be seen at Table I and Table II.…”

Section: Resultsmentioning

confidence: 77%

“…It was reported that ethanolic extract of the root bark of Cananga odorata causes spermatotoxicity in male albino rats, suppresses the production of testosterone, and alters the micronutrients of the testis [12]. The bark of Cananga odorata reveal as antibacterial and antifungal activity [13].…”

Section: Introductionmentioning

confidence: 99%

Preparing Silk Biomaterial from Cocoon of Wild Silkmoth Attacus atlas

Nindhia¹,

Nindhia²,

Surata³

et al. 2017

IJPMBS

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Abstract-This Article reporting result from research in providing silk from wild silkmoth cocoon of Attacus atlas. The silkmoth is from Indonesia origin. The research was initiated by collecting the silkmoth egg from their real location. The silkmoth eggs were hatched and the larva were introduce with specific leaf that will be use as a a future food. The consideration in selecting leaf for the food is the leaf should from the three that easily and rapid grow also having ingredient that could be useful in drug, pharmacy and medical purpose. It is found the wild silkmoth Attacus atlas are like to consume a herb plant leaf of Erythrina variegate and also Cananga odorata. The cocoon resulting from feeding the caterpillar of Attacus atlas with these 2 type of leaves were observed by using scanning electron microscope (SEM) and element compositions were detected by using Energy Dispersive X-ray Spectroscopy (EDS). Different appearance of fiber are observed. With feeding with Cananga odroata resulting fiber surface covering with cubic crystal that reach with Calcium (Ca) meanwhile feeding with Erythrina variegate resulting fiber without fibrous surface which is rich with clhorine (Cl).

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“…In our study, an increased level of testicular cholesterol and ascorbic acid in rats treated with F. limonia fruit pulp extract resulting in impaired spermatogenesis [39] . Testicular inhibitory action was further strengthened by the inhibition of testicular 吟 5 -3毬-HSD and G-6-PDH activities in rats after treated with F. limonia fruit pulp extract, as the 吟 5 -3毬-HSD and G-6-PDH are the key enzymes involved in androgen biogenesis [34,40] . Nontoxicity of extract of F. limonia fruit pulp is further supported by the data obtained after examination of haematological parameters, which remained unaltered even at the higher dose.…”

Section: Discussionmentioning

confidence: 95%

“…In our study, protein content in the testes and epididymis was significantly reduced with F. limonia fruit pulp extract, which might be a causative factor in reducing the weight of reproductive organs, sperm count and motility [2,34] . A marked reduction in the level of seminal vesicular fructose in the in F. limonia fruit pulp extract-treated rats may be another cause of reduction in sperm motility as motile sperm consume fructose after ejaculation [35] , which provided energy for sperm motility.…”

Section: Discussionmentioning

confidence: 99%