2001
DOI: 10.1046/j.1365-2605.2001.00298.x
|View full text |Cite
|
Sign up to set email alerts
|

Sperm disposal system in spermatic granuloma: a link with superoxide radicals

Abstract: Spermatic granulomas are believed to maintain "physiological harmony" in the male reproductive tract by maintaining a balance of hydrostatic pressure post-vasectomy. The mechanism for the disposal of deposited spermatozoa in the granuloma core is not clear. A fourfold rise in the production of superoxide along with ascorbyl and dienyl radicals and a 50% drop in the production of nitric oxide (NO) radicals by granuloma tissue hints that a reaction between NO and superoxide radicals could lead to the formation o… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
10
0

Year Published

2003
2003
2021
2021

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 9 publications
(10 citation statements)
references
References 40 publications
(42 reference statements)
0
10
0
Order By: Relevance
“…Increased superoxide and decreased nitric oxide are also known to be involved in SG formation (Chatterjee et al, 2001). That some inflammatory mediators may participate in 2-MI-induced SG formation is, therefore, possible.…”
Section: Discussionmentioning
confidence: 98%
“…Increased superoxide and decreased nitric oxide are also known to be involved in SG formation (Chatterjee et al, 2001). That some inflammatory mediators may participate in 2-MI-induced SG formation is, therefore, possible.…”
Section: Discussionmentioning
confidence: 98%
“…The presence of granulomas at the vasovasostomy site still does not have a conclusive meaning (25). Granulomas are described in 20 to 35% of the ducts in vasovasostomies (26).…”
Section: Commentsmentioning
confidence: 99%
“…36% of patients with granulomas had normal spermatozoa in the aspirate while only 19% of patients without granulomas had similar results. Recent experimental investigations in animal models have outlined that sperm granulomas result in a higher rate of phagocytosis of spermatozoa resulting in decreased tissue pressure in the epididymis [83].…”
Section: Sperm Granulomamentioning
confidence: 99%