Spectruophotometric Determination of Esters and Anhydrides by Hydroxamic Acid Reaction

Goddu, R. F.; Leblanc, Nicolas; Wright, Ciara

doi:10.1021/ac60104a012

Cited by 160 publications

(40 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was decided that 70 ~ would be used in future work because of the slight improvement in reproducibility as shown by the standard deviation; this is in agreement with previous research involving monoesters [9].…”

Section: Optimization Of the Hydroxamic Acid Reactionsupporting

confidence: 78%

“…Linearity of the diester-ferric hydroxamate complexes be 0.0112M. This concentration is more than double that used previously to determine monoesters [9]. Also at this time it was found that a brown precipitate formed if the concentration of the ferric perchlorate solution was too low (2.0 x 10 -4 M).…”

Section: Optimization Of the Ferric Perchlorate Reactionmentioning

confidence: 52%

“…Previously, it has been proposed [9] that monoesters are converted to hydroxamic acids by alkaline hydroxyl- amine reagent (Fig. 2, reaction).…”

Section: Proposed Reaction Mechanismmentioning

confidence: 99%

“…Goddu et al [9] investigated the spectrophotometric determination of esters and anhydrides by a ferric ion colorimetric method. The analyte is converted to a hydroxamic acid which then is reacted with ferric ion to form a purple chelate complex.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Flow injection determination of diesters as ferric hydroxamate complexes

Gallagher

Guianen²,

Pike³

et al. 1998

Mikrochim Acta

View full text Add to dashboard Cite

Abstract. Diesters such as succinylcholine chloride (SCC) and dioctylsulfosuccinate (DOSS) can be converted to hydroxamic acids which are found to react with Fe 3+ in methanol to form a purple chelate complex having an useful absorption band at 520 nm with a molar absorptivity of about 171 L/mole*cm, and a detection limit of 1.5 x 10 -4 M. To adapt this method for flow injection, a methanol-water solvent and acidification of the sample were required to reduce the large blank peak. The reproducibility of the flow injection method was a factor of two better than standard spectrophotometry but the detection limit of the former method was two times higher. This colorimetric method can permit analysis of pharmaceutical products containing either SCC or DOSS. Phosphatidylcholine (lecithin) can also be determined using this method.

show abstract

Section: Optimization Of the Hydroxamic Acid Reactionsupporting

confidence: 78%

Section: Optimization Of the Ferric Perchlorate Reactionmentioning

confidence: 52%

“…Previously, it has been proposed [9] that monoesters are converted to hydroxamic acids by alkaline hydroxyl- amine reagent (Fig. 2, reaction).…”

Section: Proposed Reaction Mechanismmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Flow injection determination of diesters as ferric hydroxamate complexes

Gallagher

Guianen²,

Pike³

et al. 1998

Mikrochim Acta

View full text Add to dashboard Cite

show abstract

“…The valuable tools for identification are mass spectrometry (Lithgow et al, 2000), nuclear magnetic resonance spectroscopy and infrared spectroscopy (Zhang et al, 1993;Debler et al, 2007;Donabedian, 2003). There is a colorimetric assay that is a modified method of the one reported by Goddu and coworkers in 1955 for the analysis of ester molecules (Goddu et al, 1955). This method can be used very quickly and easily to analyze the amount of lactone compounds and lactonase activity.…”

Section: Extraction Purification and Identificationmentioning

confidence: 99%

RETRACTED ARTICLE: Quorum-sensing of bacteria and its application

Jia

2009

J. Ocean Univ. China

View full text Add to dashboard Cite

Quorum sensing, or auto induction, as a cell density dependent signaling mechanism in many microorganisms, is triggered via auto inducers which passively diffuse across the bacterial envelope and therefore intracellulaly accumulate only at higher bacterial densities to regulate specialized processes such as genetic competence, bioluminescence, virulence and sporulation. N-acyl homoserine lactones are the most common type of signal molecules. Aquaculture is one of the fastest-growing food-producing industries, but disease outbreaks caused by pathogenic bacteria are a significant constraint on the development of the sector worldwide. Many of these pathogens have been found to be controlled by their quorum sensing systems. As there is relevance between the pathogenic bacteria's virulence factor expression and their auto inducers, quorum quenching is a new effective anti-infective strategy to control infections caused by bacterial pathogens in aquaculture. The techniques used to do this mainly include the following: (1) the inhibition of signal molecule biosynthesis, (2) blocking signal transduction, and (3) chemical inactivation and biodegradation of signal molecules. To provide a basis for finding alternative means of controlling aquatic diseases by quorum quenching instead of treatment by antibiotics and disinfectants, we will discuss the examination, purification and identification of auto inducers in this paper.

show abstract

Detection, determination and characterization

Weiler‐Feilchenfeld

1972

PATAI'S Chemistry of Functional Groups

View full text Add to dashboard Cite

Spectruophotometric Determination of Esters and Anhydrides by Hydroxamic Acid Reaction

Cited by 160 publications

References 10 publications

Flow injection determination of diesters as ferric hydroxamate complexes

Flow injection determination of diesters as ferric hydroxamate complexes

RETRACTED ARTICLE: Quorum-sensing of bacteria and its application

Detection, determination and characterization

Contact Info

Product

Resources

About