Spectrum of Chronic Complications Related to Silicone Leakage and Migration

Ryu, Alexander J.; Glazebrook, Katrina N.; Samreen, Naziya; Bauer, Philippe R.; Yi, Eunhee S.; Ryu, Jay H.

doi:10.1016/j.amjmed.2018.03.041

Cited by 18 publications

(11 citation statements)

References 8 publications

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“…Leakage and migration of silicone can also cause acute and chronic complications. It can be a local complication resulting from inflammatory foreign body reaction, referred to as “silicone granulomas” or a more distant migration or embolization of silicone including silicone lymphadenopathy [10] , silicone pneumonitis, primarily due to subcutaneous injections of silicone [2] or a systemic complication such as granuloma mediated hypercalcemia. All these complications were typically diagnosed 10 to 30 years after silicone placement [10] .…”

Section: Discussionmentioning

confidence: 99%

Late migration of silicon as a complication to breast transplant rupture: Case report and literature review

Khakbaz

Lang

Lelkaitis

et al. 2021

International Journal of Surgery Case Reports

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Silicone implants have been used for breast augmentations, both cosmetically and in reconstructive surgery since the 1960s. Rupture of breast implants and silicone migration is a well-known complication. In this case report and literature review, we present a case of a 53-year-old woman with bilateral cosmetic silicone gel breast implant in 1986, and a replacement with saline gel in 2005. The patient had no breast complaints and observed no change in breast volume during this period. In 2020, silicone was randomly identified in a right-sided cervical lymph node in an attempt to remove suspicious lymphadenopathy. The source of the silicone is still doubted; that is, it is not known if the silicone originated from the saline implant or the silicone gel implant. In our literature review, we find that distant migration of silicone and lymphadenopathy have occurred for silicone breast implants although very rare for saline gel breast implants.

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Section: Discussionmentioning

confidence: 99%

Late migration of silicon as a complication to breast transplant rupture: Case report and literature review

Khakbaz

Lang

Lelkaitis

et al. 2021

International Journal of Surgery Case Reports

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“…4,5 This complication can occur both in acute form with embolic modality and acute respiratory distress syndrome, 5,6 or chronically. 7 Respiratory symptoms are present within 72 hours after injection of higher dose silicone, but a delayed reaction is normally described up to a year and a half after injection. 5 In this scenario, the release of silicone emboli leads to occlusion of the microvasculature and triggers the inflammatory response, resulting in pulmonary edema, hemorrhage, and subsequent fibrosis.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Pulmonary Restrictive Syndrome after Liquid Silicone Injection: The Role of the Plastic Surgeon

Bonfirraro

Sallam

Verga

et al. 2021

Indian J Plast Surg

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Despite being especially used in its solid form, silicone is still injected as a liquid filler for breast contouring in many countries. Here, we present a rare case of a woman with silicone pneumonitis and extended breast scarring after breast silicone injection. Because of evidence of a restrictive syndrome due to the thoracic extensive scarring tissue and the high demand of oxygen therapy, as jointly agreed with the pulmonologists, we decided to perform a surgical asportation of the scarring tissue and covering with microsurgical flap. We chose the deep inferior epigastric perforator flap mainly because of the large amount of skin that is possible to use, the good skin texture matching, and the possibility of double team working without changing patient’s position.

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“…Silicone lymphadenopathy is a known, but rare complication of ruptured breast implants. Axillary, internal mammary (IM) and supraclavicular nodes are most commonly involved, whilst distal sites such as the mediastinum, thyroid and lung can also be affected 1,2 . This report is interesting as it presents a case of silicone lymphadenopathy demonstrating substantial short interval growth.…”

Section: Figmentioning

confidence: 94%

“…However, poor acoustic windows from overlying rib shadowing may preclude detailed assessment of IM and mediastinal nodal stations. Instead, CT can reliably identify and track growth of these lymph nodes, however is not specific for silicone 1 . Silicone‐specific MRI can also be used to characterise these nodes, although it may not exhibit high signal if nodes are variably infiltrated 3,4 .…”

Section: Figmentioning

confidence: 99%