Spectrum–effect relationship between ultra‐high‐performance liquid chromatography fingerprints and antioxidant activities of Lophatherum gracile Brongn

Abstract

Modern pharmacological studies and clinical practices have demonstrated that free radicals produced by normal organ activities will cause chain reactions after exceeding a certain amount in the body, and a series of biological reactions will eventually lead to the occurrence of a variety of diseases, such as cancer, atherosclerosis, hypertension, cataracts, arthritis, and rheumatoid arthritis (Moreno-Ortega et al., 2020;Raja et al., 2020;Wu et al., 2020). Therefore, antioxidant research has become the forefront of medical research and a hot spot for disease prevention and treatment.

Anti-inflammatory and antiviral activities of flavone C-glycosides of Lophatherum gracile for COVID-19

“…Polyphenols are phytochemicals commonly identified in L. gracile ( Liu et al, 2022 ). To qualitatively analyze the phytochemicals in LG-M, MRM experiments were performed using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) ( Fu, Wang, Lan, Li, Hashi, & Chen, 2014 ), which led to the identification of the following flavone C -glycosides: luteolin-6- C -2''-glucuronylglucoside ( 1 ), orientin ( 2 ), isoorientin ( 3 ), swertiajaponin ( 4 ), isovitexin ( 5 ), and coumaroyl quinic acids (CoQAs): 3- p -coumaroyl quinic acid ( 6 ), 4- p -coumaroyl quinic acid ( 7 ), and o -coumaroyl acid ( 8 ) ( Fig.…”

“…Lophatherum gracile ( L. gracile ) is a perennial plant that has long been used as a functional food and addictive in cosmetic products ( Lai et al, 2021 , Liu et al, 2022 ). It has been used to make facial masks, skin cream, and other healthcare products ( Lai et al, 2021 , Liu et al, 2022 ).…”

“…Lophatherum gracile ( L. gracile ) is a perennial plant that has long been used as a functional food and addictive in cosmetic products ( Lai et al, 2021 , Liu et al, 2022 ). It has been used to make facial masks, skin cream, and other healthcare products ( Lai et al, 2021 , Liu et al, 2022 ). L. gracile is the main ingredient of various teas in China, including Guangdong and Wong Lo Kat ( He et al, 2011 , Liu et al, 2022 , Liu et al, 2020 ).…”

“…It has been used to make facial masks, skin cream, and other healthcare products ( Lai et al, 2021 , Liu et al, 2022 ). L. gracile is the main ingredient of various teas in China, including Guangdong and Wong Lo Kat ( He et al, 2011 , Liu et al, 2022 , Liu et al, 2020 ). L. gracile has a long history in the treatment of fever and inflammatory conditions ( Diaz, Jeong, Lee, Khoo, & Koyyalamudi, 2012 ).…”

“…L. gracile has a long history in the treatment of fever and inflammatory conditions ( Diaz, Jeong, Lee, Khoo, & Koyyalamudi, 2012 ). Flavonoids and polyphenols are the phytochemicals commonly attributed to the anti-oxidation, anti-inflammation, anti-cancer, and pharmacological bioactivities of L. Gracile ( Chen et al, 2019 , Kim et al, 2016 , Liu et al, 2022 , Wang et al, 2012 ).…”