Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: A prospective single-center study

Abstract

This study demonstrated the prevalence of the spectrum of ophthalmologic manifestations in the IBD population, including some rare and silent findings that may merit consideration and early intervention.

Frequency of Ophthalmological Posterior Segment Findings in Patients With Inflammatory Bowel Disease

“…We found a higher incidence of ophthalmological fundoscopy findings in evaluated patients comparing to previous studies (6)(7)(8)(9)(10) . Felekis et al also found similar high prevalence of posterior segment findings, but with no differentiation between primary, secondary or coincidental findings.…”

“…Ophthalmological impairment is present in about 3.5% to 12% of IBD patients (6)(7)(8)(9) , and isn't directly correlated to intestinal mucocutaneous extension, usually occurs in IBD early years (8) . Possible ophthalmological findings are periocular edema, blepharitis, proptosis, conjunctivitis, scleritis, episcleritis, keratopathy, cataract, optic neuritis, optic, neuropathy, iridociclitis, retinal pigment epithelial atrophy, macular edema, serous retinal detachment and retinal hemorrhages (3,10) .…”

“…Episcleritis is the most frequent ophthalmological finding and it's responsible for 29% of ocular involvement, followed by scleritis, responsible for 18%, and uveitis, responsible for 17% (6,10,11) . Ophthalmological involvement can be classified as primary or directly related to IBD, which could improve after immunosuppression therapy, secondary or consequent to primary commitment, and coincidental findings, that can occur in general population and do not have direct correlation to IBD or its treatment (6,10) . Ophthalmological posterior segment findings exact prevalence is controversial.…”

A rare manifestation of Crohn’s disease in an adolescent: Optic neuritis

“…Ocular manifestation in IBD were reported in 3.5%-43% cases; interestingly, they are more common in colonic or gastric CD cases similar to our case (8). There is limited information on the ocular involvement in adolescent and pediatric patients (9).…”

Orbital pseudotumour as a presentation of paediatric ulcerative colitis

“…(3,4) Out of these, episcleritis, scleritis and uveitis are the most common ocular manifestations in adult IBD. (3,4) However, little is known of IBD in children. Although ocular manifestations usually occur early in the disease course, it is uncommon to have ocular manifestation preceding IBD diagnosis.…”