Spectroscopic, thermal and kinetic studies of coordination compounds of Zn(II), Cd(II) and Hg(II) with norfloxacin

Synthesis, structural characterization, in vitro antimicrobial and anticancer activity studies of ternary metal complexes containing glycine amino acid and the anti-inflammatory drug lornoxicam

“…The IR spectra of all complexes showed the m(C@N) stretching vibration peak at 1590-1607 cm À1 . This confirms the binding of pyridyl nitrogen to the metal ions [9][10][11][12][13][14][15][16]. The participation of the pyridyl nitrogen is difficult to be discussed as its band overlapped with those of the carboxylate group of the Gly amino acid or the amide(II) stretching vibration band.…”

“…The IR spectra of the free LOR and glycine ligands and the ternary metal complexes were carried out in the range of 4000-400 cm À1 and the most effective bands are listed in Table 2. The strong band observed at 1640 cm À1 in the free LOR ligand is assigned to the m(NHCO) stretching vibration [9][10][11][12]. This band is found in the spectra of the complexes at 1630-1659 cm À1 (Table 2) or disappeared in nickel complex indicating the participation of carbonyl oxygen atom in coordination (MAO) [9][10][11][12][13][14][15][16].…”

“…Coordination with metal ions via the carboxylate O atom and nitrogen atom indicated by the shift in position of theˆ(NH 2 ),ˆa sym (COO) andˆs ym (COO) stretching vibrations bands to 3387-3428, 1526-1599 and 1419-1430 cm À1 , respectively, for LOR-Gly-metal complexes ( Table 2). New bands of low intensity are observed in far-IR region in the range of 538-563 and 454-489 cm À1 which can be assigned toˆ(MAO) andˆ(MAN) stretching vibrations, respectively [9][10][11][12][13][14][15][16][17][18]. The metal-oxygen stretching frequencies could not be assigned unambiguously due to the presence of three types ofˆ(MAO) vibrations, i.e., MACOO À , MAH 2 O and MAC@O.…”

“…However, the data are retained in Table 2 for clarity. Therefore, from the IR spectral studies, it is concluded that LOR behaves as a neutral bidentate ligand with ON coordination sites and coordinated to the metal ions via the carbonyl oxygen and pyridyl nitrogen [9][10][11][12][13][14][15][16][17][18]. Glycine behaves as a uni-negative bidentate ligand with NO donor sites and coordinated to the metal ions via the amino group N and deprotonated carboxylic oxygen [9][10][11][12][13][14][15][16][17][18].…”

Synthesis, spectroscopic characterization, thermal analysis and electrical conductivity studies of Mg(II), Ca(II), Sr(II) and Ba(II) vitamin B2 complexes

“…Our research group has been trended in a synthesized, structural, spectroscopic characterization, thermal behavior and kinetic investigation of the thermal decomposition processes occurring through the metal ions drug interactions [16][17][18][19][20][21][22][23][24]. As a continuation in this trend, the main task of this paper is synthesized and characterizing the structures of the 1:2 metal:ligand Mg(II), Ca(II), Sr(II) and Ba(II) complexes with riboflavin and to interpretative in details its 0022-2860/$ -see front matter Ó 2011 Elsevier B.V. All rights reserved.…”