Spectroscopic, physicochemical, and pharmacokinetic analysis of α,β-amyrin mixture obtained from Protium heptaphyllum (Aubl.) Marchand resin

Oliveira, Raíssa C.; Bandeira, Paulo Nogueira; Lemos, Telma G.; Santos, Hélcio Silva dos; Julião, Murilo Sérgio da Silva; Marinho, Emmanuel Silva; Lopes, Francisco Flávio da Silva; Morais, Selene Maia de; Hora, João Pedro da; Bento, Ana Joyce de Morais; Lima, Igor Kleber Campos; Nogueira, C.E.S.; Saraiva, G.D.; Barreto, A. L. H.; Braz-Filho, Raimundo; Teixeira, Alexandre Magno Rodrigues

doi:10.1016/j.molstruc.2022.132551

Cited by 2 publications

(1 citation statement)

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“…The α and βamyrin blend has proven pharmacological properties such as antioxidant, anti-inflammatory, gastroprotective and hepatoprotective. [24][25][26] Only ethanol extracts were evaluated for total phenolic compounds and flavonoids. In the evaluation of antioxidant activities against DPPH * (2,2-Diphenyl-1-picrylhydrazyl) and ABTS + * (2,2-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) free radicals, all samples were tested, as well as to determine the inhibition of the enzyme acetylcholinesterase (AChE) (Table 4).…”

Section: Compoundsmentioning

confidence: 99%

Chemical Characterization, Phenolic Compounds Quantification, and Assessment of Antioxidant and Anti‐Acetylcholinesterase Activities of Byrsonima sericea DC fruits

da Silva Lopes,

Luís Eloi Silva,

de Morais Pereira Eloi

et al. 2024

Chemistry & Biodiversity

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Byrsonima sericea is a species native to Brazil that is widely used in traditional medicine. The seed ethanol extract (SEE) had the highest content of total phenols (179.35 mg GAE g‐1 extract) and flavonoids (10.42 mg QE g‐1 extract) and was the most active in relation to antioxidant activity (DPPH: IC50= 4.25 µg mL‐1 and ABTS: IC50= 4.82 µg mL‐1). The peel/pulp ethanol extract (PEE) had the best anticholinesterase activity (IC50= 6.02 µg mL‐1). Chromatographic investigation identified gallic acid, isoquercitrin, quercetin and amentoflavone in SEE, and gallic acid, isoquercitrin, quercetin and rutin in PEE. Six fatty acid methyl esters and seven triterpenes were identified, highlighting oleic acid in the seed hexane extract (61.85%) and in the peel/pulp hexane extract (52.61%), and betulin in the peel/pulp hexane extract (5.25%). The substances and biological activities identified in B. sericea characterize this fruit as a functional food for future studies.

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Section: Compoundsmentioning

confidence: 99%