Spectroscopic identification of S Au interaction in cysteine capped gold nanoparticles

Aryal, Santosh; B.K.C., Remant; Dharmaraj, N.; Bhattarai, Narayan; Kim, Chi Hun; Kim, Hee Young

doi:10.1016/j.saa.2005.04.048

Cited by 270 publications

(191 citation statements)

References 23 publications

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“…12,[16][17][18][19] For the protection of AgCu NAs against oxidation, cysteine which also contains the -SH group at the terminal position is preferred over other weaker binding complexing agents or stabilizers, such as oleylamines, electrostatically protecting agents or ligands containing deprotonated negatively charged carboxylic acid groups in order to suppress the oxidation of Cu 0 to Cu 2+ . For many years materials containing particles of metals such as zinc, silver and copper have been used for antibacterial applications because they have the ability to penetrate into bacteria causing cell death or interact with microbial cell membranes that cause deactivation of their activity, and in general antimicrobial activity of metals decreases with an increase in their size.…”

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confidence: 99%

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

et al. 2011

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confidence: 99%

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

et al. 2011

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“…These absorption bands were shifted to the higher wavenumbers of ~3,420 cm -1 and 1,605 cm -1 in FT-IR spectrum of FePt-Cys NPs ( Figure 3B), respectively, because of the change in the dipole moment when Cys was adsorbed on the surface of NPs with high electron density. [40][41][42] It is noteworthy that the absorption at ~2,550 cm -1 derived from the S-H stretching vibration of the Cys molecules disappeared in the FT-IR spectrum of FePt-Cys NPs (Figure 3B), indicating the interactions between Cys molecules and FePt NPs because of the high affinity of the mercapto group to the Pt atoms.…”

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Water-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma

Liang¹,

Zhou²,

Wang³

et al. 2015

IJN

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Nanoparticles (NPs) are advantageous for the delivery of diagnosis agents to brain tumors. In this study, we attempted to develop an l -cysteine coated FePt (FePt-Cys) NP as MRI/CT imaging contrast agent for the diagnosis of malignant gliomas. FePt-Cys NPs were synthesized through a co-reduction route, which was characterized by transmission electron microscopy, high-resolution transmission electron microscopy, powder X-ray diffraction, Fourier transform infrared spectroscopy, and dynamic light scattering. The MRI and CT imaging ability of FePt-Cys NPs was evaluated using different gliomas cells (C6, SGH44, U251) as the model. Furthermore, the biocompatibility of the as-synthesized FePt-Cys NPs was evaluated using three different cell lines (ECV304, L929, and HEK293) as the model. The results showed that FePt-Cys NPs displayed excellent biocompatibility and good MRI/CT imaging ability, thereby indicating promising potential as a dual MRI/CT contrast agent for the diagnosis of brain malignant gliomas.

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“…33−35 Surface modification of the silica shell usually involves covalent attachment; therefore, this avoids cysteine residue replacement of thiol ligands, which is often used in gold or silver surface functionalization. 36 In the present study, Au/Ag/SiO 2 −NRs were synthesized and tested for SPORT experiments. Millisecond/submillisecond temporal resolution was achieved in imaging the fast dynamics of Au/Ag/SiO 2 −NRs rotating on synthetic lipid membranes and live cell membranes.…”

Section: * S Supporting Informationmentioning

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Multishell Au/Ag/SiO₂ Nanorods with Tunable Optical Properties as Single Particle Orientation and Rotational Tracking Probes

et al. 2015

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Three-layer core-shell plasmonic nanorods (Au/Ag/SiO 2-NRs), consisting of a gold nanorod core, a thin silver shell, and a thin silica layer, were synthesized and used as optical imaging probes under a differential interference contrast microscope for single particle orientation and rotational tracking. The localized surface plasmon resonance modes were enhanced upon the addition of the silver shell, and the anisotropic optical properties of gold nanorods were maintained. The silica coating enables surface functionalization with silane coupling agents and provides enhanced stability and biocompatibility. Taking advantage of the longitudinal LSPR enhancement, the orientation and rotational information of the hybrid nanorods on synthetic lipid bilayers and on live cell membranes were obtained with millisecond temporal resolution using a scientific complementary metal-oxide-semiconductor camera. The results demonstrate that the as-synthesized hybrid nanorods are promising imaging probes with improved sensitivity and good biocompatibility for single plasmonic particle tracking experiments in biological systems.Keywords biocompatibility, cell membranes, coupling agents, cytology, image processing, lipid bilayers, MOS devices, nanorods, optical properties, plasmons, probes, silanes, silica, silver, surface plasmon resonance, anisotropic optical properties, complementary metal oxide semiconductors, differential interference contrast microscopes, localized surface plasmon resonance, plasmonic particles, silane coupling agent, tunable optical properties, chemistry, light related phenomena, molecular probe, tumor cell line, nanotubes, optical phenomena Disciplines Chemistry CommentsReprinted (adapted) with permission from Analytical Chemistry 87 (2015) ABSTRACT: Three-layer core−shell plasmonic nanorods (Au/Ag/SiO 2 −NRs), consisting of a gold nanorod core, a thin silver shell, and a thin silica layer, were synthesized and used as optical imaging probes under a differential interference contrast microscope for single particle orientation and rotational tracking. The localized surface plasmon resonance modes were enhanced upon the addition of the silver shell, and the anisotropic optical properties of gold nanorods were maintained. The silica coating enables surface functionalization with silane coupling agents and provides enhanced stability and biocompatibility. Taking advantage of the longitudinal LSPR enhancement, the orientation and rotational information of the hybrid nanorods on synthetic lipid bilayers and on live cell membranes were obtained with millisecond temporal resolution using a scientific complementary metal-oxide-semiconductor camera. The results demonstrate that the as-synthesized hybrid nanorods are promising imaging probes with improved sensitivity and good biocompatibility for single plasmonic particle tracking experiments in biological systems.S

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Spectroscopic identification of S Au interaction in cysteine capped gold nanoparticles

Cited by 270 publications

References 23 publications

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

Water-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma

Multishell Au/Ag/SiO₂ Nanorods with Tunable Optical Properties as Single Particle Orientation and Rotational Tracking Probes

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Spectroscopic identification of S Au interaction in cysteine capped gold nanoparticles

Cited by 270 publications

References 23 publications

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

Synthesis, characterization and antibacterial investigation of silver–copper nanoalloys

Water-soluble l-cysteine-coated FePt nanoparticles as dual MRI/CT imaging contrast agent for glioma

Multishell Au/Ag/SiO2 Nanorods with Tunable Optical Properties as Single Particle Orientation and Rotational Tracking Probes

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Multishell Au/Ag/SiO₂ Nanorods with Tunable Optical Properties as Single Particle Orientation and Rotational Tracking Probes