Spectroscopic evidence for cis‐[PtCl2(NH3)2]‐erythrocyte membrane interaction

Hörer, O; Nicolau, Claude

doi:10.1016/0014-5793(71)80632-4

Cited by 5 publications

(1 citation statement)

References 3 publications

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“…However, it is also possible that the platinum may interact with some components of the cell membrane or cell-wall related material (our present knowledge of the chemical properties of the palmelloid matrix is limited) before entering tbe cell. Tbis was suggested by a spectroscopic study of cK-dicblorodiamine platinum (Il)-erythrocyte membrane interaction (Horer and Nicolau 1971). More information on the cbemistry of various complexes of platinum with nucleic acid and with membrane should shed some light on this problem.…”

Section: Discussionmentioning

confidence: 99%

Chemical Factors Affecting Palmelloid‐Forming Activity of Chloroplatinic Acid on Chlamydomonas eugametos

Nakamura

Sakon

Hatanaka

1976

Physiologia Plantarum

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In order to elucidate the physiological mechanism of palmelloid formation of the unicellular green alga Chlamydomonas eugametos by chloroplatinic acid, the factors causing inhibition of the palmelloid formation were studied in various media. Chloroplatinic acid lost its palmelloid‐forming effect in the presence of nitrite ion and amines having a second functional group. Nitrate, potassium, and sodium ions and monofunctional amines were without influence on the effect of chloroplatinic acid. These results indicate that the active form of platinum (IV) may undergo ligand substitution, the resulting complex being unable to cause palmelloid formation.

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Section: Discussionmentioning

confidence: 99%