Spectrophotometric Micro determination of Silver(I) using Meloxicam as a New Analytical Reagent

Abstract

A new chromogenic reagent, meloxicam was used for highly sensitive, selective and rapid method for the determination of silver based on the rapid reaction of silver(I) with meloxicam. In the presence acetate buffer solution of pH 4.6 and Triton X-100 as an optimum medium, meloxicam reacts with silver to form a yellow complex of molar ratio 1:1 (silver to meloxicam). The molar absorptivity of the formed complex was calculated to be 1.124 x 10 4 L mol -1 cm -1 at 412 nm. Beer's law is obeyed in the range of 1.0-15.0 µg mL -1 . The relative standard deviation for six replicate samples of 7.0 µg mL -1 was 1.33%. The limits of detection and quantification were also calculated. Finally the repeatability, accuracy and the effect of interfering ions on the determination of silver ion were evaluated. The method was applied successfully for determination silver in some water samples.

Ag0–Ginger Nanocomposites Integrated into Natural Hydrogelated Matrices Used as Antimicrobial Delivery Systems Deposited on Cellulose Fabrics

“…Specimens from each cotton fabric finished with natural hydrogel loaded with the Ag 0 -ginger nanocomposite were evaluated regarding the antifungal and antibacterial activity by the "Agar diffusion plate test" (Table 3). According to the method presented in the literature [52,53] and in ISO 20645:2004 [54], each fabric sample was placed on a wet culture of microbial cells. The samples were moistened, and the silver ions diffused, reaching the culture of bacteria/fungi, where they affected their growth more or less in relation to the concentration of ions released from the multicomponent system.…”

Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet

“…Meloxicam Figure1, is a newer non-steroidal anti-inflammatory drug (NSAID) in the enolic acid group found to inhibit cyclo-oxygenase -2(cox-2) [1], it is used to treatment of ankylosing spondylitis, osteoarthritis and rhenumatoid arthritis [2]. Meloxicam drug was used to prepare nano crystal formulation to increase transdermal delivery [3], also made films nano crystals from meloxicam [4] and using meloxicam as an analytical reagent for determination silver and vanadium [5,6]. There are many analytical methods were reported for the estimation meloxicam in biological and pharmaceutical samples they include: flow-injection chemiluminescence [7], liquid-chromatography-tan-dem mass spectrometry [8], polarographic [9], flow injection spectrophotometric [10,11], fluorimetric [12] and derivative spectrophotometric methods [13].…”