Spectro-Magnetic and Antimicrobial Studies on some 3d Metal Complexes with Ethylenedianil of Ortho-Hydroxyphenylglyoxal

Abstract

The Cr(III), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes with a novel tetradentate ligand obtained by condensation of ethylenediamine with ortho-hydroxyphenylglyoxal have been synthesized and characterized by elemental analysis, molar conductance and magnetic susceptibility measurements, IR, UV-Visible and atomic absorption studies. The Cr(III), Fe(III) and Co(II) complexes possess six coordinate octahedral geometry whereas Ni(II), Cu(II) and Zn(II) complexes are square planar and tetrahedral respectively. Bactericidal and fungicidal activities of the compounds were evaluated in vitro by disc diffusion method. The perusal of antimicrobial activities of the compounds reveals that the complexes possess greater bactericidal and fungicidal activities against all the microbes in comparison to ligand which is due to their higher lipophilicity.

Chemical Preparation, Spectro-Magnetic and Biocidal Studies on Some Divalent Transition Metal Complexes of Schiff’s Base Derived from 1-Phenyl-2-(Pyridin-2-yl)ethane-1,2-dione and Ethylenediamine

“…suggestive of distorted octahedral nature for the complex [14]. Zn(II) complex does not demonstrate any characteristic d-d transitions and besides found to be diamagnetic in nature [12].…”

“…The spectral parameters of Co (II) complex are as follows [14]: Dq = 1036.8 cm T 1g (F) transitions in an octahedral field [5]. The transition due to 3 A 2g (F) → 3 T 1g (P) was completely obscured by the intense intra ligand transition band [12]. The spectral parameters of the Ni(II)complex are as follows [14] : Dq = 1036.27 cm T 2g transition suggesting the distorted octahedral geometry [13].…”

“…and appearance of a new band in 488-561 cm -1 attributed to vM-O reveal the bands that occur in the low wavenumbers range were assigned to the stretching vibrations ν(M-O) coordination of the ligand [12]. The band(s) at 1605-1630 cm -1 due to the azomethine group of the Schiff 's base ligand underwent a shift to lower frequency (1570-1600 cm -1 ) after complex formation, indicating the coordination of azomethine nitrogen to metal atom and this can be explained by the donation of electrons from nitrogen to the empty d-orbitals of the metal atom.…”

Antimicrobial, Antioxidant and DNA Interaction Studies of Water-soluble Complexes of Schiff Base Bearing Morpholine Moiety

“…The π system in a Schiff base often imposes a geometrical constriction and influences the electronic structure as well. Schiff base ligands and their metal complexes have been extensively studied over the past few decades and the relevant transition metal complexes are still found to be a great curiosity in inorganic chemistry due to various biological activities [4] . Das et al studied the successful treatment of persistent bronchorrhea by gefitinib established remarkable cytotoxic potencies towards human HL-60 leukemic cells [5] .…”

“…The present study aimed to investigate the reaction of tridentate Schiff base ligand (HL) derived from the condensation of 4-(2-aminoethyl)-morpholine with salicylaldehyde. The complexes (1)(2)(3)(4)(5) were synthesized by the ligand (HL) coordinating to Cu(II), Co(II), Mn(II), Ni(II) and Zn(II) ions. The complexes (1)(2)(3)(4)(5) were more stable with good solubility in common solvents like water and methanol.…”