Spectral-Domain Optical Coherence Tomography Angiography Findings in Multifocal Choroiditis With Active Lesions

Cheng, Lijun; Chen, Xia; Weng, Sisi; Mao, Lei; Gong, Yuanyuan; Yu, Shizhu; Xu, Xun

doi:10.1016/j.ajo.2016.06.029

Cited by 53 publications

(51 citation statements)

References 24 publications

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“…OCTA can help in distinguishing these inflammatory foci from iCNVs that commonly complicate MFC. In fact, MFC lesions do not show any internal flow on OCTA, in contrast to iCNV where blood flow is clearly visible within the neovascular network …”

Section: Oct/octa Of the Outer Retina Retinal Pigment Epithelium Andmentioning

confidence: 88%

“…In most OCTA scans, iCNV appears as a well‐circumscribed neovascular network, typically located at the level of the avascular zone (outer retina RPE) . Due to alterations in the normal anatomy of the retinal layers induced by the exudative process, the use of automated segmentation software can fail .…”

Section: Oct/octa Of Inflammatory Choroidal Neovascularizationmentioning

confidence: 99%

“…In fact, MFC lesions do not show any internal flow on OCTA, in contrast to iCNV where blood flow is clearly visible within the neovascular network. 58 Different mechanisms, including RPE dysfunction, choroidal outflow impairment, breakdown of the outer BRB, and leakage from iCNVs can lead to the accumulation of 4 Subretinal fluid can be easily visualized and monitored with structural OCT, but usually it is not suggestive of a specific aetiology. However, the presence of hyper-reflective septa and the consequent formation of pockets of fluid within the subretinal space is strongly suggestive for acute VKH disease ( Figure 9D).…”

Section: Oct/octa Of the Outer Retina Retinal Pigment Epithelium Amentioning

confidence: 99%

“…In most OCTA scans, iCNV appears as a wellcircumscribed neovascular network, typically located at the level of the avascular zone (outer retina RPE). 58,69,71 Due to alterations in the normal anatomy of the retinal layers induced by the exudative process, the use of automated segmentation software can fail. 74 Manual adjustments of the reference segmentation line and plane are often necessary to accurately define the neovascular network and differentiate it from superficial retinal vessels and underlying choroidal structures.…”

Section: Oct/octa Of Inflammatory Choroidal Neovascularizationmentioning

confidence: 99%

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Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

Invernizzi

Cozzi

Staurenghi

2019

Clinical Exper Ophthalmology

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Optical coherence tomography (OCT) has dramatically changed the understanding and management of uveitis and other ocular conditions. Currently, OCT angiography (OCTA) combines structural information with the visualization of blood flow within the imaged area. The aim of this review is to present the basic principles of OCT and OCTA interpretation and to investigate the role of these imaging techniques in the diagnosis and management of uveitis. Common complications of intraocular inflammation such as macular oedema and inflammatory choroidal neovascularization are often diagnosed and followed with OCT/OCTA scans. However, uveitis specialists can obtain much more information from tomographic scans. This review provides a comprehensive description of typical OCT/OCTA findings characterizing different ocular structures in uveitis, proceeding from the cornea to the choroid. A careful interpretation of OCT/OCTA images can help in the differential diagnosis, the prediction of clinical outcomes, and the follow‐up of patients with uveitis.

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Section: Oct/octa Of the Outer Retina Retinal Pigment Epithelium Andmentioning

confidence: 88%

Section: Oct/octa Of Inflammatory Choroidal Neovascularizationmentioning

confidence: 99%

Section: Oct/octa Of the Outer Retina Retinal Pigment Epithelium Amentioning

confidence: 99%

Section: Oct/octa Of Inflammatory Choroidal Neovascularizationmentioning

confidence: 99%

See 2 more Smart Citations

Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

Invernizzi

Cozzi

Staurenghi

2019

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

show abstract

“…In birdshot chorioretinopathy, OCT-A highlighted decreased choroidal blood flow and retinal capillary density in the superficial and deep plexuses,21 22 while the studies about the other two aforementioned diseases analysed the choroidal neovascular inflammatory complication. Cheng et al 23 described choroidal neovascularization (CNV) in MFC as a well-circumscribed vascular network, while most of the inflammatory lesions showed no blood flow in the outer retinal layer. Furthermore, in studies conducted by Levison et al and Zahid et al ,24 25 OCT-A clearly identified CNVs in MFC/PIC and showed remodelling of the shape of the lesion after anti-vascular endothelial growth factor treatment.…”

Section: Discussionmentioning

confidence: 99%