Swept-source optical coherence tomography angiography in serpiginous choroiditis

Montorio, Daniela; Giuffrè, Chiara; Miserocchi, Elisabetta; Modorati, Giulio; Sacconi, Riccardo; Mercuri, Stefano; Querques, Lea; Querques, Giuseppe; Bandello, Francesco

doi:10.1136/bjophthalmol-2017-310989

Cited by 28 publications

(12 citation statements)

References 24 publications

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“…Swept-source optical coherence tomography (SS-OCT) uses a longer wavelength than spectral domain OCT, penetrates tissues better and enables us to visualise the choroid 3 . Choroidal changes are evaluated in various systemic 4 and ocular [5][6][7][8][9][10][11] disorders.…”

Section: Introductionmentioning

confidence: 99%

Changes in subfoveal choroidal thickness after uncomplicated cataract surgery

Gudauskienė¹,

Matulevičiūtė²,

Mockutė³

et al. 2019

BIOMED PAP

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Background. Recent investigations show that phacoemulsification causing an inflammatory insult to the eye has an effect not only on retina but on the choroid as well. The purpose of this study was to evaluate the subfoveal choroidal thickness (SFCT) after uneventful phacoemulsification using swept-source optical coherence tomography (SS-OCT). Methods. This prospective study included 30 eyes of 23 patients with senile cataract undergoing uncomplicated phacoemulsification and intraocular lens implantation. SFCT and foveal retinal thickness (FRT) measurements were made at the same time, 1-2 PM preoperatively (P), 1 month (M1) and 3 months (M3) postoperatively using 1050 nm DRI Triton SS-OCT (Topcon, Tokyo, Japan). Postoperative changes in the SFCT, FRT and correlation of SFCT change with axial length, age, baseline intraocular pressure (IOP), IOP change were assessed. Results. The mean SFCT increased statistically significantly 3 months after surgery in all sectors except the superior inner region. Of the factors affecting the SFCT, the change in the SFCT (M3/P), correlation with age and baseline IOP in almost all sectors was observed. The mean FRT increased significantly after the surgery in all sectors. Conclusions. Insignificant subclinical increase in SFCT was observed 1 month after the cataract surgery. Significant increment in SFCT was detected 3 months postoperatively, which was correlated with surgery-induced IOP and ocular perfusion pressure change in the short term.

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Section: Introductionmentioning

confidence: 99%

Changes in subfoveal choroidal thickness after uncomplicated cataract surgery

Gudauskienė¹,

Matulevičiūtė²,

Mockutė³

et al. 2019

BIOMED PAP

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“…According to the literature, hypoautofluorescent lesions with hyperautofluorescent borders were to be expected in active disease [21][22][23]. The study of Montorio et al found a complete loss of detectable flow in 2 active eyes with SC, whereas choroidal vessel rarefaction and loss of choriocapillaris could be seen in inactive eyes (20 eyes) [31].…”

Section: Discussionmentioning

confidence: 99%

“…Another hypothesis is that this effect can be a consequence of the absence of or different flow (e.g. too slow or too fast) or characteristics of the vessels and surrounding tissues within these regions due to inflammation as first proposed by Montorio et al [31].…”

Section: Discussionmentioning

confidence: 99%

Optical coherence tomography angiography (OCTA) findings in Serpiginous Choroiditis

et al. 2020

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Background: To describe changes in the retina/choroid in patients with Serpiginous Choroiditis (SC) by Optical Coherence Tomography Angiography (OCTA) in a multimodal imaging approach. Methods: Prospective, monocentric study of 24 eyes of 12 consenting patients diagnosed with SC, who underwent OCTA, which was analyzed and compared to other methods such as enhanced depth imaging-OCT, fluorescein angiography, indocyanine green angiography, and fundus autofluorescence. Results: The study group consisted of 9 patients with peripapillary SC, 1 macular SC, and 2 atypical cases. All eyes presented an inactive SC confirmed by standard imaging. OCTA demonstrated the lesions tridimensionally in great detail. There was no difference in the angioarchitecture among the 3 forms of SC. A loss of the choriocapillaris/retinal pigment epithelium left a "window-defect", where the vessels of larger caliber of the choroid became recognizable and their appearance inverted ("white-on-black"). A relationship between the presence of segmentation errors (SE) in the slabs and low visual acuity was established with a one-way ANOVA. Conclusions: OCTA was able to non-invasively assess vascular lesions of the choroid/retina in patients with SC with a high degree of correlation to other diagnostic modalities. Consequent long-term assessments could lead to a better understanding of disease progression.

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“…2a, b). On both FFA/ICGA perfusion defects of the choriocapillaris seem to be more extensive than the RPE damage shown on FAF, which suggests that choroidal damage precedes RPE damage [80,82]. OCTA of choriocapillaris on active lesions shows clearly demarcated flow-deficit areas that correspond precisely to the hypofluorescent lesions on ICGA [82,83].…”

Section: Punctate Inner Choroidopathymentioning

confidence: 99%

“…On both FFA/ICGA perfusion defects of the choriocapillaris seem to be more extensive than the RPE damage shown on FAF, which suggests that choroidal damage precedes RPE damage [80,82]. OCTA of choriocapillaris on active lesions shows clearly demarcated flow-deficit areas that correspond precisely to the hypofluorescent lesions on ICGA [82,83]. Conversely, inactive lesions demonstrate some detectable flow within the areas of flow void, indicating deeper medium-to-large choroidal vessels existence and choriocapillaris loss, better detected on OCTA than on ICGA [23,84,85].…”

Section: Punctate Inner Choroidopathymentioning

confidence: 99%

Optical coherence tomography angiography in uveitis

Tranos¹,

Karasavvidou

Gkorou³

et al. 2019

J Ophthal Inflamm Infect

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Before the introduction of optical coherence tomography angiography (OCTA) in the early 2000s, dye-based angiography was considered the "gold standard" for the diagnosis and monitoring of ocular inflammation. OCTA is a novel technique, which demonstrates capillary networks based on the amount of light returned from moving blood cells, providing further information on pathophysiological changes in uveitis. The aim of this review is to describe the basic principles of OCTA and its application to ocular inflammatory disorders. It particularly emphasizes on its contribution not only in the diagnosis and management of the disease but also in the identification of possible complications, comparing it with fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Although the advent of OCTA has remarkably enhanced the assessment of uveitic entities, we highlight the need for further investigation in order to better understand its application to these conditions.

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Swept-source optical coherence tomography angiography in serpiginous choroiditis

Abstract: OCT-A represents a new imaging technique that provides useful information about the leading changes of choroidal vascular network in active and inactive lesions of SC.

Cited by 28 publications

References 24 publications

Changes in subfoveal choroidal thickness after uncomplicated cataract surgery

Changes in subfoveal choroidal thickness after uncomplicated cataract surgery

Optical coherence tomography angiography (OCTA) findings in Serpiginous Choroiditis

Optical coherence tomography angiography in uveitis

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