SPECT Myocardial Blood Flow Quantitation Concludes Equivocal Myocardial Perfusion SPECT Studies to Increase Diagnostic Benefits

Abstract

Recently, myocardial blood flow quantitation with dynamic SPECT/CT has been reported to enhance the detection of coronary artery disease in human. This advance has created important clinical applications to coronary artery disease diagnosis and management for areas where myocardial perfusion PET tracers are not available. We present 2 clinical cases that undergone a combined test of 1-day rest/dipyridamole-stress dynamic SPECT and ECG-gated myocardial perfusion SPECT scans using an integrated imaging protocol and demonstrate that flow parameters are capable to conclude equivocal myocardial perfusion SPECT studies, therefore increasing diagnostic benefits to add value in making clinical decisions.

Clinical Application of Dynamic SPECT/CT in a Patient with Prior Myocardial Infarction Underwent Percutaneous Coronary Intervention Twice

“…Nevertheless, cardiac PET imaging has limitations due to high cost and sometimes low cyclotron availability. Hsu et al reported the use of dynamic SPECT/CT to measure absolute MBF to enhance CAD detection and diagnosis [2,4]. According to this case, we found that dynamic SPECT/CT could provide much earlier information in terms of flow parameters to rescue the jeopardized myocardium in post-PCI evaluation.…”