Abstract:BackgroundMyocardial damage caused by diabetic cardiomyopathy results in cardiac structural and functional abnormalities. Our previous studies have demonstrated that inhibiting RhoA/ROCK signaling pathway improved the structural abnormalities. The early detection of cardiac functional alterations accompanied by structural changes during therapy may facilitate better understanding on the pathophysiologic progress and guiding diabetic cardiomyopathy treatment. This study aimed to identify the optimal diagnostic … Show more
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