SPECIFIC FEATURES OF AXIAL SKELETON INVOLVEMENT IN EARLY PSORIATIC ARTHRITIS (The REMARCA TRIAL)

Логинова, Е. Ю.; Коротаева, Т. В.; Смирнов, А. В.; Глазков, А. А.; Каратеев, Д. Е.; Насонов, Е. Л.

doi:10.14412/1995-4484-2016-1s-15-19

Cited by 7 publications

(7 citation statements)

References 14 publications

(16 reference statements)

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“…Логиновой и соавт. [13], изучавших данную проблему на 40 больных. Настоящая работа -продолжение этого исследования.…”

Section: Discussionunclassified

“…Настоящая работа -продолжение этого исследования. Наши данные, полученные на большем клиническом материале, подтверждают результаты предшествующей работы [13], в которой было показано, что поражение осевого скелета при ПсА часто протекает малосимптомно, что приводит к его недостаточной диагностике.…”

Section: Discussionunclassified

“…Логиновой и соавт. [13]), но выявили корреляцию между МРТ-СИ и ограничением функции позвоночника, а также между наличием активного воспаления КПС и длительностью заболевания. Вероятно, имеющиеся различия в результатах связаны с разными сроками заболевания у пациентов в нашем исследовании и в работе L. Williamson и соавт.…”

Section: Discussionunclassified

“…Логиновой и соавт. [13], которые показали, что среди больных ранним ПсА частота носительства антигена HLA-B27 составила 42,5% (в нашей когорте больных -38%). Несмотря на то что МРТ-СИ и рдСИ несколько чаще выявлялись у больных, имевших антиген HLA-B27, ассоциация HLA-B27 с МРТ-СИ (Q=0,53; Phi=0,26) и рдСИ (Q=0,56) была незначимой.…”

Section: Discussionunclassified

“…Логиновой и соавт. [13]. В нашей работе обнаружена ассоциация между наличием СИ, выявленного любым из методов визуализации, и ВБС.…”

Section: Discussionunclassified

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Clinical and Instrumental Characteristics of Axial Lesion in Early Peripheral Psoriatic Arthritis (Data of a Remarca Study)

Gubar¹,

Логинова²,

Смирнов³

et al. 2018

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Section: Discussionunclassified

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Clinical and Instrumental Characteristics of Axial Lesion in Early Peripheral Psoriatic Arthritis (Data of a Remarca Study)

Gubar¹,

Логинова²,

Смирнов³

et al. 2018

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Psoriatic arthritis: pathogenetic features and innovative therapies

Лила¹,

Насонов

Коротаева³

2019

Naučno-praktičeskaâ revmatologiâ

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The paper considers the modern concepts of the etiology and pathogenesis of psoriatic arthritis (PsA). The latter is currently indicated as a T-cell-mediated disease that is based on the activation of cellular immunity, followed by the hyperproduction and imbalance of key pro- and anti-inflammatory cytokines, such as tumor necrosis factor-α (TNF- α), interleukin-1β (IL-1β), IL-6, IL-12/23, and IL-17. The paper presents the basic principles of diagnosis and clinical manifestations of the disease and notes the importance of screening questionnaires, the use of which allows specialists to diagnose PsA early, by actively identifying articular complaints, the characteristic clinical and radiological signs of damage to the joint, spine, and entheses. It is pointed out that the key target of pharmacotherapy for PsA is to achieve remission or minimal activity of the main clinical manifestations of the disease, to slow down or prevent its radiographic progression, to increase the length and quality of life in patients, and to reduce the risk of comorbidities. The authors characterize the major groups of used drugs: nonsteroidal anti-inflammatory drugs, conventional and targeted synthetic disease-modifying antirheumatic drugs, and biological drugs (inhibitors of TNF-α, IL-12/23, and IL-17). The key Treat-to-target principles of patient management are considered; it is noted that strict control over disease activity and treatment results provides suppression of all major clinical manifestations of PsA. The paper also shows the basic principles of the creation and further development of the All-Russian Registry of PsA patients, which makes it possible to optimize management decision-making on the provision of high-tech medical care and drugs for this cohort of patients.

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Comparative characteristics of early psoriatic arthritis with and without axial skeleton injury (a subanalysis of the all-Russian registry of patients with psoriatic arthritis)

Gubar¹,

Логинова²,

Коротаева³

et al. 2019

Naučno-praktičeskaâ revmatologiâ

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SPECIFIC FEATURES OF AXIAL SKELETON INVOLVEMENT IN EARLY PSORIATIC ARTHRITIS (The REMARCA TRIAL)

Cited by 7 publications

References 14 publications

Clinical and Instrumental Characteristics of Axial Lesion in Early Peripheral Psoriatic Arthritis (Data of a Remarca Study)

Clinical and Instrumental Characteristics of Axial Lesion in Early Peripheral Psoriatic Arthritis (Data of a Remarca Study)

Psoriatic arthritis: pathogenetic features and innovative therapies

Comparative characteristics of early psoriatic arthritis with and without axial skeleton injury (a subanalysis of the all-Russian registry of patients with psoriatic arthritis)

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