Special Hematologic Issues in the Pregnant Patient

Rizack, Tina; Perez, Kimberly; Strenger, Rochelle

doi:10.1007/978-1-4614-1244-1_7

Cited by 3 publications

(3 citation statements)

References 69 publications

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“…During pregnancy, changes occur and can be observed in CBC. Some of the parameters are decreased like Hb and PLT, and others are increased like WBC . The aim of the study was to describe the variation of CBC during pregnancy and determine the appropriate reference intervals for pregnant women.…”

Section: Discussionmentioning

confidence: 99%

Establishment of reference intervals for complete blood count parameters during normal pregnancy in Beijing

Yang

Zhang

et al. 2017

Clinical Laboratory Analysis

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Section: Discussionmentioning

confidence: 99%

Establishment of reference intervals for complete blood count parameters during normal pregnancy in Beijing

Yang

Zhang

et al. 2017

Clinical Laboratory Analysis

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“…Pregnancy alone increases the risk of thromboembolism by a factor of 4 to 5, and this risk is doubled with Cesarean delivery. 16 Coexisting hematologic malignancy markedly exacerbates the risk of leukocytosis, deep vein thrombosis, and disseminated coagulopathy; it also increases the risk of placental thrombosis or insufficiency, which can result in low birth weight. Prophylactic administration of low-molecular-weight heparin is considered to be safe for pregnant patients at high risk.…”

Section: Discussionmentioning

confidence: 99%

“…Exercise extreme caution; use where benefit to mother clearly outweighs risk to fetus. Vincristine 1,11,16,45 No congenital anomalies or neurotoxicity documented.…”

Section: 28mentioning

confidence: 99%

Management of Concurrent Pregnancy and Acute Lymphoblastic Malignancy in Teenaged Patients: Two Illustrative Cases and Review of the Literature

Zaidi

Johnson

Church

et al. 2014

Journal of Adolescent and Young Adult Oncology

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The usual age range of acute lymphoblastic malignancies (acute lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma) includes teenagers and young adults (<22 years of age) and coincides with the age of fertility. Concurrence of acute lymphoblastic malignancy with pregnancy is therefore most likely to happen during the younger childbearing ages. However, the therapeutic challenges posed by the dual diagnosis of lymphoblastic malignancy and pregnancy have not specifically been studied in the context of age, and management guidelines for pregnant young patients are lacking. Inconsistency in defining the legal decision-making rights of pregnant teenaged patients adds a further level of complexity in this age group. Management of this challenging combination in the young patient therefore entails unique ethical considerations. Here we present two illustrative cases of teenage pregnancy complicated by acute lymphoblastic malignancy, review the available literature, and offer suggestions for the therapeutic management of such cases in adolescent and young adult patients. Importantly, practical management recommendations are provided in the context of clinical ethics principles that are universally applicable, including in developing countries, where the highest incidence of adolescent pregnancies has been documented.

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Successful treatment of acute lymphoblastic leukemia (ALL) during pregnancy using a pediatric-based protocol incorporating pegylated asparaginase

Jeffrey

Presgrave

Walsh

et al. 2023

Leukemia & Lymphoma

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Special Hematologic Issues in the Pregnant Patient

Cited by 3 publications

References 69 publications

Establishment of reference intervals for complete blood count parameters during normal pregnancy in Beijing

Establishment of reference intervals for complete blood count parameters during normal pregnancy in Beijing

Management of Concurrent Pregnancy and Acute Lymphoblastic Malignancy in Teenaged Patients: Two Illustrative Cases and Review of the Literature

Successful treatment of acute lymphoblastic leukemia (ALL) during pregnancy using a pediatric-based protocol incorporating pegylated asparaginase

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