Spatial patterns in prostate Cancer-specific mortality in Pennsylvania using Pennsylvania Cancer registry data, 2004–2014

Wang, Ming; Wasserman, Emily; Geyer, Nathaniel R.; Carroll, Rachel; Zhao, Shanshan; Zhang, Lijun; Hohl, Raymond J.; Lengerich, Eugene J.; McDonald, Alicia C.

doi:10.1186/s12885-020-06902-5

Cited by 8 publications

(15 citation statements)

References 45 publications

(46 reference statements)

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“…Further, there are interactions between these risk factors, particularly with those involving the environment [ 13 , 14 ], whose spatial variation may lead to heterogeneity in the pattern of cancers in a given geographic catchment area. Studies by Wang et al [ 15 , 16 ] found a significant spatial variation of prostate cancer incidence and prostate cancer-specific mortality in Pennsylvania, USA. They evaluated potential effects of individual and county-level risk factors and found that spatial variations in prostate cancer-specific mortality rates existed in Pennsylvania with a particularly high risk in the Pen State catchment area.…”

Section: Introductionmentioning

confidence: 99%

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014 to 2017

et al. 2020

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Background The most common gender-specific malignancies are cancers of the breast and the prostate. In developing countries, cancer screening of all at risk is impractical because of healthcare resource limitations. Thus, determining high-risk areas might be an important first screening step. This study explores incidence patterns of potential high-risk clusters of breast and prostate cancers in southern Iran. Methods This cross-sectional study was conducted in the province of Kerman, South Iran. Patient data were aggregated at the county and district levels calculating the incidence rate per 100,000 people both for cancers of the breast and the prostate. We used the natural-break classification with five classes to produce descriptive maps. A spatial clustering analysis (Anselin Local Moran’s I) was used to identify potential clusters and outliers in the pattern of these cancers from 2014 to 2017. Results There were 1350 breast cancer patients (including, 42 male cases) and 478 prostate cancer patients in the province of Kerman, Iran during the study period. After 45 years of age, the number of men with diagnosed prostate cancer increased similarly to that of breast cancer for women after 25 years of age. The age-standardised incidence rate of breast cancer for women showed an increase from 29.93 to 32.27 cases per 100,000 people and that of prostate cancer from 13.93 to 15.47 cases per 100,000 during 2014–2017. Cluster analysis at the county level identified high-high clusters of breast cancer in the north-western part of the province for all years studied, but the analysis at the district level showed high-high clusters for only two of the years. With regard to prostate cancer, cluster analysis at the county and district levels identified high-high clusters in this area of the province for two of the study years. Conclusions North-western Kerman had a significantly higher incidence rate of both breast and prostate cancer than the average, which should help in designing tailored screening and surveillance systems. Furthermore, this study generates new hypotheses regarding the potential relationship between increased incidence of cancers in certain geographical areas and environmental risk factors.

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Section: Introductionmentioning

confidence: 99%

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014 to 2017

et al. 2020

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“…Further, there are interactions between these risk factors, particularly with those involving the environment (13,14), whose spatial variation may lead to heterogeneity in the pattern of cancers in a given geographic catchment area. Studies by Wang et al (15,16) found a signi cant spatial variation of prostate cancer incidence and prostate cancer-speci c mortality in Pennsylvania, USA. They evaluated potential effects of individual and county-level risk factors and found that spatial variations in prostate cancer-speci c mortality rates existed in Pennsylvania with a particularly high risk in the Pen State catchment area.…”

Section: Introductionmentioning

confidence: 99%

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014-2017

Montazeri

Hoseini

Firouraghi

et al. 2020

Preprint

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Background:The most common gender-specific malignancies are cancers of the breast and the prostate. In developing countries, cancer screening of all at risk is impractical because of healthcare resource limitations. Thus, determining high-risk areas might be an important first screening step. This study explores incidence patterns of potential high-risk clusters of breast and prostate cancers in southern Iran.Methods:This cross-sectional study was conducted in the province of Kerman, South Iran. Patient data were aggregated at the county and district levels calculating the incidence rate per 100,000 people both for cancers of the breast and the prostate. We used the natural-break classification with five classes to produce descriptive maps. A spatial clustering analysis (Anselin Local Moran’s I) was used to identify potential clusters and outliers in the pattern of these cancers from 2014 to 2017.Results:There were 1,350 breast cancer patients (including, 42 male cases) and 478 prostate cancer patients in the province of Kerman, Iran during the study period. After 45 years of age, the number of men with diagnosed prostate cancer increased similarly to that of breast cancer for women after 25 years of age. The age-standardised incidence rate of breast cancer for women showed an increase from 29.93 to 32.27 cases per 100,000 people and that of prostate cancer from 13.93 to 15.47 cases per 100,000 during 2014-2017. Cluster analysis at the county level identified high-high clusters of breast cancer in the north-western part of the province for all years studied, but the analysis at the district level showed high-high clusters for only two of the years. With regard to prostate cancer, cluster analysis at the county and district levels identified high-high clusters in this area of the province for two of the study years.Conclusions:North-western Kerman had a significantly higher incidence rate of both breast and prostate cancer than the average, which should help in designing tailored screening and surveillance systems. Furthermore, this study generates new hypotheses regarding the potential relationship between increased incidence of cancers in certain geographical areas and environmental risk factors.

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“…There is a spatial variation in environmental risk factors and this variation may lead to heterogeneity in the pattern of cancers in a given geographic catchment area. Studies by Wang et al (2017) and Wang et al (2020) found a signi cant spatial variation of prostate cancer incidence and prostate cancer-speci c mortality in Pennsylvania, USA. They evaluated potential effects of individual and county-level risk factors and found that spatial variations in prostate cancer-speci c mortality rates existed in Pennsylvania with a particularly high risk in the Pen State catchment area (15,16).…”

mentioning

confidence: 99%

“…Studies by Wang et al (2017) and Wang et al (2020) found a signi cant spatial variation of prostate cancer incidence and prostate cancer-speci c mortality in Pennsylvania, USA. They evaluated potential effects of individual and county-level risk factors and found that spatial variations in prostate cancer-speci c mortality rates existed in Pennsylvania with a particularly high risk in the Pen State catchment area (15,16). County-level health and environmental factors might contribute to spatial heterogeneity in prostate cancer-speci c mortality in the study area.…”

mentioning

confidence: 99%

Spatio-temporal Mapping of Breast and Prostate Cancer in South Iran During 2014-2017

Montazeri

Hoseini

Firouraghi

et al. 2020

Preprint

View full text Add to dashboard Cite

Abstract Background: Breast and prostate cancers are the most common gender-specific malignancies. In developing countries, screening of all population at risk of cancers is impractical because of the healthcare resource limitations. Thus, determining the high-risk areas of Cancers might be an important step to conduct a screening program at high-risk areas. This study explores potential high-risk clusters in the incidence pattern of breast and prostate cancers in southern Iran. Methods: This cross-sectional study was conducted in the province of Kerman, South Iran. Patient data were aggregated at the county and district levels and the incidence rate per 100,000 people for both breast and prostate cancer were calculated. We used the natural break classification with five classes to produce descriptive maps. A spatial clustering analysis ( Anselin Local Moran’s I ) was used to identify potential clusters and outliers in the pattern of these cancers from 2014 to 2017. Results: The Age-Standardised Incidence Rate of breast cancer showed an increase from 29.93 to 32.27 cases per 100,000 people and prostate cancer from 13.93 to 15.47 cases per 100,000 during 2014–2017. Cluster analysis at the county level identified high-high clusters of breast cancer in the North-West of the province for all years, but the analysis at the district level showed high-high clusters for only two of the years. Furthermore, cluster analysis at the county and district levels of prostate cancer also identified high-high clusters in the North-West of the province for two years. Conclusions: North-West Kerman had a significantly higher incidence rate of both breast and prostate cancer. These findings may help to design tailored screening and surveillance systems. Furthermore, this study generates new hypotheses to test potential relationships between environmental risk factors and incidence of cancers in areas with higher cancer risk.

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Spatial patterns in prostate Cancer-specific mortality in Pennsylvania using Pennsylvania Cancer registry data, 2004–2014

Cited by 8 publications

References 45 publications

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014 to 2017

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014 to 2017

Spatio-temporal mapping of breast and prostate cancers in South Iran from 2014-2017

Spatio-temporal Mapping of Breast and Prostate Cancer in South Iran During 2014-2017

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