Sparing of photic frequency and brightness discriminations after striatectomy in neonatal cats.

Tucker, Thomas J.; Kling, Arthur; Scharlock, Donald P.

doi:10.1152/jn.1968.31.6.818

Cited by 33 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, Tucker, Kling, and Scharlock (1968) have reported that combined removal of Areas 17, 18, and 19 and suprasylvian gyri plus superior colliculi in infancy significantly impairs the discrimination of photic frequency taught at maturity, a deficit not found after cortical lesion alone.…”

Section: Brightness Discrimination In the Catmentioning

confidence: 83%

Pretectum and superior colliculus in visually guided behavior and in flux and form discrimination in the cat.

Berlucchi¹,

Sprague²,

Levy³

et al. 1972

Journal of Comparative and Physiological Psychology

132

View full text Add to dashboard Cite

Adult split-brain cats with unilateral ablation of pretectum and/or superior oolliculus were trained monocularly in flux and form discriminations. When the midbrain lesions involved both colliculus and pretectum, there was a severe impairment in learning pattern discriminations using the eye on the lesion side. In those cases with the lesions chiefly in the colliculus or in pretectum the deficit was present but less marked. When these same discriminations were taught before the midbrain lesion, no loss in retenlion was found postoperatively.

show abstract

Section: Brightness Discrimination In the Catmentioning

confidence: 83%

Pretectum and superior colliculus in visually guided behavior and in flux and form discrimination in the cat.

Berlucchi¹,

Sprague²,

Levy³

et al. 1972

Journal of Comparative and Physiological Psychology

132

View full text Add to dashboard Cite

show abstract

“…LGN cell size A striking feature of the LGNs of KVC-ID and KVC-8WK cats is the presence of many large surviving cells that are not present in AVC cats (Table 1, row 2) (Doty, 196 1;Wetzel et al, 1965;Tucker et al, 1968;Mize and Murphy, 1976;Cornwell et al, 1978;Murphy and Kalil, 1979;Kalil, 1984). However, we found no functional correlate of this difference in LGN cell size.…”

Section: Relationship Of Results Tomentioning

confidence: 99%

“…The LGN layers are more shrunken and distorted, and the overall volume of the nucleus is smaller. However, in addition to small neurons that survive the degeneration, many large, darkly staining neurons survive in all LGN layers (Doty, 1961;Wetzel et al, 1965;Tucker et al, 1968;Mize and Murphy, 1976;Cornwell et al, 1978;Murphy and Kalil, 1979;Kalil, 1984). These large surviving neurons are abundant in the LGN following a visual cortex lesion made as late as 18 weeks of age (unpublished observations), but very few are present following a lesion made in adult animals.…”

mentioning

confidence: 99%

Responses of lateral geniculate neurons that survive long-term visual cortex damage in kittens and adult cats

et al. 1989

View full text Add to dashboard Cite

Damage to visual cortex (areas 17-19) in kittens or adult cats produces severe retrograde degeneration of neurons in the dorsal lateral geniculate nucleus (LGN). However, some neurons survive in otherwise degenerated portions of the LGN after a visual cortex lesion at any age. Previous studies have shown that there are well-defined differences in potential retinal inputs, soma size, synaptic connections, outputs, and physiological properties of output targets of the surviving LGN cells in cats that received visual cortex damage at different ages. The present experiment investigated the relationships between these differences and the responses of surviving LGN neurons to visual stimulation. Recordings were made from surviving neurons in the degenerated A- and C-layers of the LGN in cats that had received a visual cortex lesion on the day of birth, at 8 weeks of age, or as adults (survival was 11.5-36 months). Normal adult cats were studied for comparison. The visual receptive field was mapped, and tests were carried out to classify each cell as X, Y, or W. In addition, quantitative methods were used to assess response amplitude, strength of receptive-field surround inhibition, spatial-frequency tuning to drifting or counterphased sine-wave gratings, and response to nondominant-eye stimulation for each cell. We found that surviving cells in all LGN layers respond to light, have normal receptive-field organization, and have normal eye dominance following a lesion at any age tested. In addition, gross retinotopic organization of the LGN is normal. However, 2 main abnormalities were observed following a lesion at all 3 ages. First, there is a reduction in the percentage of X cells in the A layers, from 62% in normal LGNs to about 15% in degenerated LGNs. Second, many surviving cells in both the A- and C-layers have abnormally large receptive-field centers. Other differences that were observed between normal A-layer cells and surviving A-layer cells could be attributed to the loss of X cells. These results indicate that cells within a structure that shows severe retrograde degeneration after brain damage can maintain relatively normal function and can take part in potentially important residual neural pathways. Previous studies indicate that these residual pathways can show both anatomical and physiological compensation for the brain damage, and the present findings bear on the consequences and mechanisms of this compensation.

show abstract

“…lead to minor deficits in direction processing in PMLS cortex as assessed by neuronal response properties~Tong et al, 1984;Guido et al, 1990a! and behavioral testing~Wetzel et al, 1965Tucker et al, 1968;Murphy et al, 1975;Cornwell & Payne, 1989!. This sparing may be caused by an increase of and0or novel projections to PMLS cortex from the lateral geniculate nucleus~LGN!…”

Section: Introductionmentioning

confidence: 99%

Complex motion selectivity in PMLS cortex following early lesions of primary visual cortex in the cat

et al. 2007

View full text Add to dashboard Cite

In the cat, the analysis of visual motion cues has generally been attributed to the posteromedial lateral suprasylvian cortex (PMLS) (Toyama et al., 1985; Rauschecker et al., 1987; Rauschecker, 1988; Kim et al., 1997). The responses of neurons in this area are not critically dependent on inputs from the primary visual cortex (VC), as lesions of VC leave neuronal response properties in PMLS relatively unchanged (Spear & Baumann, 1979; Spear, 1988; Guido et al., 1990b). However, previous studies have used a limited range of visual stimuli. In this study, we assessed whether neurons in PMLS cortex remained direction-selective to complex motion stimuli following a lesion of VC, particularly to complex random dot kinematograms (RDKs). Unilateral aspiration of VC was performed on post-natal days 7-9. Single unit extracellular recordings were performed one year later in the ipsilateral PMLS cortex. As in previous studies, a reduction in the percentage of direction selective neurons was observed with drifting sinewave gratings. We report a previously unobserved phenomenon with sinewave gratings, in which there is a greater modulation of firing rate at the temporal frequency of the stimulus in animals with a lesion of VC, suggesting an increased segregation of ON and OFF sub-regions. A significant portion of neurons in PMLS cortex were direction selective to simple (16/18) and complex (11/16) RDKs. However, the strength of direction selectivity to both stimuli was reduced as compared to normals. The data suggest that complex motion processing is still present, albeit reduced, in PMLS cortex despite the removal of VC input. The complex RDK motion selectivity is consistent with both geniculo-cortical and extra-geniculate thalamo-cortical pathways in residual direction encoding.

show abstract

Sparing of photic frequency and brightness discriminations after striatectomy in neonatal cats.

Cited by 33 publications

References 0 publications

Pretectum and superior colliculus in visually guided behavior and in flux and form discrimination in the cat.

Pretectum and superior colliculus in visually guided behavior and in flux and form discrimination in the cat.

Responses of lateral geniculate neurons that survive long-term visual cortex damage in kittens and adult cats

Complex motion selectivity in PMLS cortex following early lesions of primary visual cortex in the cat

Contact Info

Product

Resources

About