2001
DOI: 10.1053/hupa.2001.28244
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SPARC expression in primary human renal cell carcinoma: Upregulation of SPARC in sarcomatoid renal carcinoma

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Cited by 45 publications
(33 citation statements)
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“…In addition, patients with lower SPARC expression had an improved prognosis. A similar clinicpathologic relationship between SPARC expression and tumour progression has been reported in other malignancies (Porte et al, 1995;Massi et al, 1999;Thomas et al, 2000;Sakai et al, 2001;Yamanaka et al, 2001;Yamashita et al, 2003). The expression of SPARC has been positively correlated with the histological grade of tumour cells in bladder cancer, thyroid cancer, glioma and HCC (Le Bail et al, 1999;Menon et al, 2000;Takano et al, 2000;Yamanaka et al, 2001).…”
Section: Discussionmentioning
confidence: 49%
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“…In addition, patients with lower SPARC expression had an improved prognosis. A similar clinicpathologic relationship between SPARC expression and tumour progression has been reported in other malignancies (Porte et al, 1995;Massi et al, 1999;Thomas et al, 2000;Sakai et al, 2001;Yamanaka et al, 2001;Yamashita et al, 2003). The expression of SPARC has been positively correlated with the histological grade of tumour cells in bladder cancer, thyroid cancer, glioma and HCC (Le Bail et al, 1999;Menon et al, 2000;Takano et al, 2000;Yamanaka et al, 2001).…”
Section: Discussionmentioning
confidence: 49%
“…The expression of SPARC has been positively correlated with the histological grade of tumour cells in bladder cancer, thyroid cancer, glioma and HCC (Le Bail et al, 1999;Menon et al, 2000;Takano et al, 2000;Yamanaka et al, 2001). Higher SPARC expression was also associated with local tumour invasion in colorectal, breast, bladder and renal cell carcinoma (Porte et al, 1995;Sakai et al, 2001;Yamanaka et al, 2001;Iacobuzio-Donahue et al, 2002). Increased levels of SPARC were associated with lymph node metastasis in colorectal and oesophageal cancers, liver metastasis in colorectal cancer and bone metastasis in prostate cancers (Porte et al, 1995;Thomas et al, 2000;Yamashita et al, 2003).…”
Section: Discussionmentioning
confidence: 99%
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“…However, in situ hybridization has demonstrated the high expression of SPARCL1 in angiogenic endothelial cells in the stromal areas of invasive pancreatic adenocarcinoma (15). Moreover, SPARC genes have been found overexpressed in melanomas (16) and renal carcinoma (17). Additionally, in colorectal carcinoma, where SPARCL1 was found highly expressed, its upregulation appeared to act as a pro-angiogenic stimulus (18).…”
Section: Discussionmentioning
confidence: 99%