Spanih Validation of TOOL Questionnaire: A New Instrument to Assess Quality of Life in Patients with Schizophrenia and Bipolar Disorder

Montejo, Ángel L.; Correas-Lauffer, Javier; Porras, Floryana-Maria Viquez; Martin, T.; Carrasco, P.R.; Cordero, Luis; Díez, Teresa; Mauriño, Jorge

doi:10.1016/s0924-9338(09)71180-0

Cited by 2 publications

(1 citation statement)

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“…The TOOL [15][16][17][18], a specific measure to assess Table 2. Definition of psychometric properties.…”

Section: Health Related Quality Of Life Questionnaire (Hrqol)mentioning

confidence: 99%

Patient Reported Outcomes Instruments in Schizophrenia: A Review of Psychometric Properties

Millier¹,

Clay²,

Charaf³

et al. 2014

OJMP

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Background: Interest in the self-perception of patients with mental illness is increasing because of the gap between the physician and patient perceptions of symptoms and drug side effects. Schizophrenia is one of the mental illnesses that cause the greatest difficulty in understanding the various physical and psychological impacts related to both symptoms and drug treatment. Thus, several patient-reported outcomes (PRO) have been developed to get a clearer understanding of patients' experience with their own illness and the treatment that they receive. Objective: The aim of this study was to identify all PRO questionnaires used in the evaluation of patients with schizophrenia, and to assess the quality of these questionnaires based on psychometric evidence. Methods: All PRO questionnaires used in the evaluation of patients with schizophrenia were identified using a search strategy in Pubmed, Medline, and the ISPOR website. PRO psychometric properties were extracted, and their level of validation was assessed. Results: The literature search resulted in the identification of 70 generic, mental health-specific or schizophrenia-specific instruments. These questionnaires were categorized according to measured domains. Six major domains were identified: health related quality of life (HRQoL), insight, depression/ feelings, treatment related, illness symptoms, and caregiver/family. Questionnaires measuring other dimensions were classified as other (related to personality measurement, communication between patients and clinicians and services satisfaction). The review shows that the HRQoL questionnaires demonstrate the best psychometric properties. Conclusion: The assessments of these questionnaires, based on their psychometric evidence level, will allow researchers to choose the most appropriate PRO instruments, based on the instruments' ability to respond to the objectives of the study and on the rigor of their psychometric qualities. As schizophrenia is a multidimensional mental illness, we argue that a single PRO questionnaire is insufficient to obtain a clear understanding of the condition and treatment effects in patients with schizophrenia. Thus, we think that new PRO instruments in schizophrenia should be developed.

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“…The TOOL [15][16][17][18], a specific measure to assess Table 2. Definition of psychometric properties.…”

Section: Health Related Quality Of Life Questionnaire (Hrqol)mentioning

confidence: 99%

Patient Reported Outcomes Instruments in Schizophrenia: A Review of Psychometric Properties

Millier¹,

Clay²,

Charaf³

et al. 2014

OJMP

View full text Add to dashboard Cite

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Health related quality of life in patients having schizophrenia negative symptoms – a systematic review

Azaiez

Millier

Lançon

et al. 2018

Journal of Market Access & Health Policy

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Background: Schizophrenia negative symptoms (SNS) contribute substantially to poor functional outcomes, loss in productivity and poor quality of life. It is unclear which instruments may be used for assessing quality of life in patients with SNS.Objective: The objective of this review was to identify instruments assessing health-related quality of life (HRQoL) validated in patients with SNS and to assess their level of validation.Data sources: We conducted a systematic literature review in Medline and the ISPOR database in March 2016 to identify studies on the quality of life in patients with SNS published by March 2016.Data extraction: Psychometric properties and validation steps.Data synthesis: After applying inclusion/exclusion criteria, 49 studies were selected for the analysis of HRQoL instruments; however, none of these instruments only addressed patients with SNS. Of these, 19 HRQoL instruments used in patients with schizophrenia or including patients with SNS among others, in the context of instrument validation, were identified (4 generic, 10 non-specific mental health, 5 schizophrenia-specific).Conclusion: No HRQoL instrument has been validated in patients with SNS only; for the remaining instruments identified, it remains unclear whether they were intended to capture HRQoL in patients with SNS.

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Spanih Validation of TOOL Questionnaire: A New Instrument to Assess Quality of Life in Patients with Schizophrenia and Bipolar Disorder

Cited by 2 publications

References 0 publications

Patient Reported Outcomes Instruments in Schizophrenia: A Review of Psychometric Properties

Patient Reported Outcomes Instruments in Schizophrenia: A Review of Psychometric Properties

Health related quality of life in patients having schizophrenia negative symptoms – a systematic review

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