Sorption of Phenobarbital and Amobarbital on Na-montmorillonite

Abstract

In order to characterize the sorption kinetics of phenobarbital sodium and amobarbital sodium on natural Na � montmorillonite, the influence of the initial drug concentration and clay particles sizes was investigated. Equilibrium isotherms have been measured and analyzed using a Langmuir isotherm model. The affinity of drugs sorbed onto clay varied in the following descending order: phenobarbital sodium ] amobarbital sodium, respectively 11.2 and 9.1 mg/g. Also, sorption of phenobarbital sodium and amobarbital sodium on Na-montmorillonite was studied as a function of pH. The results show that adsorption of the drugs is highest below the pHZPC due the neutrality of the drugs which adsorbs via an attraction of the positively charged surface sites at lower pH by weak van der Waals forces.

Influence of Internal Structure of the Sorbents on Diazepam Sorption from Simulated Intestinal Fluid

“…Additionally, three different particle sizes of natural Na-montmorillonite (D < 2 µm; 4 µm < D < 6 µm; 8 µm < D < 10 µm) were used for sorption of diazepam. In this case, the initial diazepam SIF solution concentration was 18 mg/L [7].…”

“…In a previous study we have determined pore size distribution, pore volume and surface area of natural Na-montmorillonite [7].…”

“…Activated charcoal and bentonite are frequently used for the treatment of the poisoned persons especially as a household remedy [7]. Activated charcoal (AC) is obtained by wood or other carbonaceous material pyrolysis, followed by the oxidation of the pyrolyzed product with carbon dioxide or steam.…”

“…These cations form outer-sphere surface complexes [14] and can be exchanged with other cations existing in solute. Furthermore, montmorillonite is characterized by pH-dependent sorption properties [7].…”

Optimizing Enzymatic Biodegradation of Skins Waste Using Response Surface Methodology

“…Raw hide waste resulting from fleshing, splits and pelt trimming, proteins from the solution exhausted from liming can be used for biochemical processing in the form of proteins [4][5][6]. Collagen, keratin and fat, contained in hide can be biodegraded of enzymes, such as lipases, oxidereductase and protease that can be used to obtaining of hydrolisates with many possibilities of capitalization, for example obtaining biofertilisers with complex composition, biostimulators [7][8][9].…”