Sonography‐assisted cutting needle biopsy in the head and neck for the diagnosis of lymphoma: Can it replace lymph node extirpation?

Abstract

CNB proved to be a sufficient alternative to open biopsy with excellent diagnostic yield and clinical usefulness. We recommend this procedure as the initial diagnostic step in patients with suspected lymphoma, either at presentation or at recurrence, and advocate its use in peripheral lymphadenopathy of the neck.

Can cutting-needle biopsy be an alternative to excisional biopsy in lymph node pathologies?

“…There was no difference in core length median value have been reported. In a study by Demharter et al, 89% sensitivity and 97% specificity for malignant lymphomas were reported (15), while Pfeiffer and colleagues provided rates of 89.7% and 100%, respectively, with a diagnostic accuracy rate of 93.3% (12). In our study, we found 90% sensitivity and 100% specificity of CnBs on enlarged lymph nodes.…”

“…recent developments in histopathological and especially immunohistochemical examination have changed the CnB approach and made it possible to make a diagnosis even in small tissue specimens (8,11,15). CnB allows the enlarging lymph nodes to be distinguished not just as benign or malignant, but can even lead to diagnoses of the HL and nHL subtypes (12). Subtyping of some lymphomas can be very difficult with CnB but subtyping in excisional biopsies may also be impossible (8).…”

Image-guided core needle biopsy in the diagnosis of malignant lymphoma

“…10 For these reasons, the demand for less invasive methods of tissue sampling has led to the introduction of image-guided biopsy techniques including FNAC and CNB. 11 Performed blind or under imaging guidance, FNAC is a minimally invasive procedure that is fast, relatively inexpensive and well-tolerated by most patients. 12 It has high reported levels of sensitivity and specificity, particularly when sampling head/neck lesions.…”

Ultraschall in der Diagnostik maligner Lymphome

“…Zur Klärung unklarer Lymphadenopathien wird bei Kindern zunächst eine Feinnadelaspirationsbiopsie favorisiert [29]. Eine endgültige Klassifikation des malignen Lymphomsubtyps mittels Schneidbiopsie im Halsbereich wurde mit 92,2% (n=45) beschrieben [18], bei abdominellen Lymphomen mit 87%. Eine zusätzliche Lymphknotenexstirpation war im Regelfall nicht notwendig [35].…”