Sonoelastographic lesion stiffness: preoperative predictor of the presence of an invasive focus in nonpalpable DCIS diagnosed at US-guided needle biopsy

Abstract

Sonoelastographic lesion stiffness is an independent preoperative predictor of invasion in some patients with nonpalpable DCIS at US-guided needle biopsy.

Sonoelastography for 1786 non-palpable breast masses: diagnostic value in the decision to biopsy

“…The previous study reported that the mean elasticity score of intraductal papillomas was higher than that of benign proliferative lesions (2.9±1.0 vs. 1.7±0.9, respectively) (P<0.01) [2]. However, contrary to their results showing no difference in elasticity scores between DCIS and IDC, we found that the mean elasticity score of IDC was higher than that of DCIS (3.26±0.09 vs. 2.54±0.11, respectively) (P<0.001), which is similar to the results of another study [17].…”

Quantitative Maximum Shear-Wave Stiffness of Breast Masses as a Predictor of Histopathologic Severity

“…Because invasive cancers tend to be stiffer than DCIS lesions, homogeneous stiffness on strain elastography predicted an increased likelihood of an upgrade to invasive carcinoma at excision after a core biopsy showing DCIS in one series [25]. We confirmed that DCIS is softer, on average, than invasive breast cancer, with a median Emax of 126 kPa for DCIS versus 180 kPa for invasive cancers (p = 0.002) in our series.…”

Usefulness of ultrasound elastography in reducing the number of Breast Imaging Reporting and Data System category 3 lesions on ultrasonography

“…This result can be explained by the fact that DCIS tends to show less suspicious features than invasive cancers on B-mode ultrasonography [22], tending to be classified as BI-RADS category 3. Furthermore, as DCIS is softer than invasive cancers [16], it is more difficult to distinguish DCIS from benign lesions than to distinguish invasive cancers from benign lesions on US elastography. In a previous study using the same elasticity score as our study, although the mean elasticity score of DCIS was higher than that of benign disease (2.54±0.11 vs. 1.78±0.81; P<0.001), the mean elasticity score of DCIS was lower than that of invasive ductal carcinomas (2.54±0.11 vs. 3.26±0.09; P<0.001) [14].…”