Sonodynamic cancer therapy by a nickel ferrite/carbon nanocomposite on melanoma tumor: In vitro and in vivo studies

Gorgizadeh, M.; Azarpira, Negar; Lotfi, Mehrzad; Daneshvar, Fatemeh; Salehi, Fatemeh; Sattarahmady, N.

doi:10.1016/j.pdpdt.2019.05.023

Cited by 46 publications

(17 citation statements)

References 48 publications

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“…Ultrasound, a typical high-frequency mechanical wave, can also be used as an external energy source. Gorgizadeh et al synthesized a nickel ferrite/carbon nanocomposite (NiFe 2 O 4 /C) as sonosensitizer (Gorgizadeh et al, 2019). Radiation of ultrasound into NiFe 2 O 4 /C effectively induced cavitation formation and ROS production, resulting in remarkable efficacious recovery in mouse melanoma cancer model by intratumorally injection at dosage of ∼100 mg kg −1 .…”

Section: External Field Enhanced Fenton Reactionmentioning

confidence: 99%

Ferrite Nanoparticles-Based Reactive Oxygen Species-Mediated Cancer Therapy

Zhang

et al. 2021

Front. Chem.

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Ferrite nanoparticles have been widely used in the biomedical field (such as magnetic targeting, magnetic resonance imaging, magnetic hyperthermia, etc.) due to their appealing magnetic properties. In tumor acidic microenvironment, ferrite nanoparticles show intrinsic peroxidase-like activities, which can catalyze the Fenton reaction of hydrogen peroxide (H2O2) to produce highly toxic hydroxyl free radicals (•OH), causing the death of tumor cell. Recent progresses in this field have shown that the enzymatic activity of ferrite can be improved via converting external field energy such as alternating magnetic field and near-infrared laser into nanoscale heat to produce more •OH, enhancing the killing effect on tumor cells. On the other hand, combined with other nanomaterials or drugs for cascade reactions, the production of reactive oxygen species (ROS) can also be increased to obtain more efficient cancer therapy. In this review, we will discuss the current status and progress of the application of ferrite nanoparticles in ROS-mediated cancer therapy and try to provide new ideas for this area.

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Section: External Field Enhanced Fenton Reactionmentioning

confidence: 99%

Ferrite Nanoparticles-Based Reactive Oxygen Species-Mediated Cancer Therapy

Zhang

et al. 2021

Front. Chem.

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“…Combining magnetic nanomaterials with other functional nanomaterials has been widely used in cancer diagnosis and treatment. In a recent study, a nickel ferrite/carbon nanocomposite (NiFe2O4/C) which combined multiple diagnostic and therapeutic functions, i.e., MRI, magnetic drug delivery, hyperthermia, and SDT was synthesized [128]. Under US (1.0 W/cm 2 ), NiFe2O4/C can produce a large amount of ROS.…”

Section: Metal Nanostructures-based Sonosensitizersmentioning

confidence: 99%

Recent advances in nanomaterials for sonodynamic therapy

et al. 2020

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Sonodynamic therapy (SDT), as a novel non-invasive strategy for eliminating tumor, has the advantages of deeper tissue penetration, fewer side effects, and better patient compliance, compared with photodynamic therapy (PDT). In SDT, ultrasound was used to activate sonosensitizer to produce cytotoxic reactive oxygen species (ROS), induce the collapse of vacuoles in solution, and bring about irreversible damage to cancer cells. In recent years, much effort has been devoted to developing highly efficient sonosensitizers which can efficiently generate ROS. However, the traditional organic sonosensitizers, such as porphyrins, hypericin, and curcumins, suffer from complex synthesis, poor water solubility, and low tumor targeting efficacy which limit the benefits of SDT. In contrast, inorganic sonosensitizers show good in vivo stability, controllable physicochemical properties, ease of achieving multifunctionality, and high tumor targeting, which greatly expanded their application in SDT. In this review, we systematically summarize the nanomaterials which act as the carrier of molecular sonosensitizers, and directly produce ROS under ultrasound. Moreover, the prospects of inorganic nanomaterials for SDT application are also discussed.

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“…The NiFe 2 O 4 /C nanocomposite not only caused ROS generation under US irradiation but also mediated the cavitation process. They stated that the synergistic cytotoxic effects of NiFe 2 O 4 /C nanocomposite plus US irradiation were due to hyperthermia and ROS generation [ 635 ]. The same researchers in a similar study fabricated MnFe 2 O 4 and a carbon nanocomposite (MnFe 2 O 4 /C) for photothermal therapy, sonodynamic therapy, and MR imaging contrast enhancement for melanoma.…”

Section: Reviewmentioning

confidence: 99%

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

Fateh¹,

Moradi²,

Kohan³

et al. 2021

Beilstein J. Nanotechnol.

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The field of theranostics has been rapidly growing in recent years and nanotechnology has played a major role in this growth. Nanomaterials can be constructed to respond to a variety of different stimuli which can be internal (enzyme activity, redox potential, pH changes, temperature changes) or external (light, heat, magnetic fields, ultrasound). Theranostic nanomaterials can respond by producing an imaging signal and/or a therapeutic effect, which frequently involves cell death. Since ultrasound (US) is already well established as a clinical imaging modality, it is attractive to combine it with rationally designed nanoparticles for theranostics. The mechanisms of US interactions include cavitation microbubbles (MBs), acoustic droplet vaporization, acoustic radiation force, localized thermal effects, reactive oxygen species generation, sonoluminescence, and sonoporation. These effects can result in the release of encapsulated drugs or genes at the site of interest as well as cell death and considerable image enhancement. The present review discusses US-responsive theranostic nanomaterials under the following categories: MBs, micelles, liposomes (conventional and echogenic), niosomes, nanoemulsions, polymeric nanoparticles, chitosan nanocapsules, dendrimers, hydrogels, nanogels, gold nanoparticles, titania nanostructures, carbon nanostructures, mesoporous silica nanoparticles, fuel-free nano/micromotors.

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Sonodynamic cancer therapy by a nickel ferrite/carbon nanocomposite on melanoma tumor: In vitro and in vivo studies

Cited by 46 publications

References 48 publications

Ferrite Nanoparticles-Based Reactive Oxygen Species-Mediated Cancer Therapy

Ferrite Nanoparticles-Based Reactive Oxygen Species-Mediated Cancer Therapy

Recent advances in nanomaterials for sonodynamic therapy

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

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