Some Properties of an Antibiotic Obtained from a Species of
            <i>Streptomyces</i>

Gottlieb, David; Bhattacharyya, P.; Anderson, H. W.; Carter, H. E.

doi:10.1128/jb.55.3.409-417.1948

Cited by 60 publications

(8 citation statements)

References 4 publications

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“…Nevertheless, the phylogenetic distance between H. influenzae and E. cloacae NfsB proteins suggests to us that chloramphenicol reduction may be relatively widely spread. Chloramphenicol is a natural product antibiotic that has been recovered from across the globe (Ehrlich et al, 1947;Gottlieb and Bhattacharyya, 1948) and is detectable in the soil at low concentrations (Berendsen et al, 2013), suggesting that nitroreduction may be a feasible resistance mechanism against environmental levels of the drug.…”

Section: Discussionmentioning

confidence: 99%

Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol

Crofts

Sontha

King

et al. 2019

Cell Chemical Biology

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Section: Discussionmentioning

confidence: 99%

Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol

Crofts

Sontha

King

et al. 2019

Cell Chemical Biology

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“…In nature, nitroaromatic compounds are mostly found in natural products from different plants, fungi, and bacteria [5,6]. The best known example of this is chloramphenicol, which is produced by Streptomyces venezuelae [7][8][9]. The role of some nitroaromatic compounds in cellular signaling has also been established.…”

Section: Nitroaromaticsmentioning

confidence: 99%

Bioremediation of Nitroaromatic Compounds

Singh¹,

Mishra²,

Ramanthan³

2015

Wastewater Treatment Engineering

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Nitroaromatics are major pollutants released in the environment during the post-industrialization era and pose toxic effects to living organisms. Several bacterial strains have been isolated for the degradation of these nitroaromatic pollutants. Some of them have been used in field trial experiments for the removal of nitroaromatics from industrial water and groundwater. Very few bacterial pathways have been characterized at genetic and molecular levels. In this review, we cover all reported degradation pathways and their gene evolution. These studies for nitroaromatics clearly indicate that most of the involved genes have evolved from preexisting enzymes by using all means of gene evolution like horizontal gene transfer, mutation, and promiscuity principle. This information has been exploited for the creation of hybrid pathways and better biocatalysts for degradation.

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“…Susceptibility of strains of S. venezuelae, S. griseus, and S. lavendulae to actinophagecontaining culture filtrates of some of these strains* LYSIS OF AGAR PLATE SEEDINGS OF * Except as otherwise noted, these teests were made by Robert M. (Gottlieb et al, 1948) obtained lysis. which it had been isolated, but none of the tested strains of other actinomycete species.…”

Section: Tablementioning

confidence: 99%

Streptomyces venezuelae, N. Sp., the Source of Chloromycetin

Ehrlich

Gottlieb

Burkholder

et al. 1948

Journal of Bacteriology

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rThe Streptomyces that produces "chloromycetin" differs from those described in Bergey's Manual (BIeed ct al., 1948) and is therefore believed to be a new species for which the name Streptomyccs venezuelae is proposed. Two cultures have been sttudied, the first one isolated at New Haven (Burkholder no. A65) from a soil sample collected in a mulched field near Caracas, Venezuela, the second one isolated at Urbana (Gottlieb no. 8-44) from a compost soil on the horticultural farm of the Illinois Agricultural Experiment Station at Urbana

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Some Properties of an Antibiotic Obtained from a Species of Streptomyces

Cited by 60 publications

References 4 publications

Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol

Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol

Bioremediation of Nitroaromatic Compounds

Streptomyces venezuelae, N. Sp., the Source of Chloromycetin

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