Some polyelectrolytic properties of polyvinylphosphonic acid and its copolymers

Levin, Ya. A.; Романов, В. Г.; Ivanov, B.Ye.

doi:10.1016/0032-3950(75)90257-9

Cited by 5 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is followed by a steeper increase in pH with increasing α until the limiting value is reached, which represents the dissociation of one of the hydroxyl groups of the phosphonic acid. These results are in agreement with previous literature on the topic, which have demonstrated that while the VPA monomer shows the two dissociation steps expected; PVPA behaves as a monoprotic acid. , …”

Section: Resultssupporting

confidence: 93%

“…These results are in agreement with previous literature on the topic, which have demonstrated that while the VPA monomer shows the two dissociation steps expected; PVPA behaves as a monoprotic acid. 22,31 As opposed to the homopolymers, the titration curves of the copolymers show two neutralization steps, which may be attributed to the contributions of VPA with a pK a1 of 2.49 (step 1) and AA with a pK a2 of 7.74 (step 2). However, these steps are not very distinct and it was shown by Bingol et al 22 that even in the presence of low molecular weight salt (NaCl), it is not possible to discern two clear dissociation steps.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…where I CH , I CH 2 , and I CHCH 2 are the integrals under the CH, CH 2 and CHCH 2 peaks, respectively. 31 P NMR spectra were recorded in solution (5 wt % in D 2 O) on a Bruker AV500 spectrometer operating at 202.48 MHz. The 31 P NMR spectra were referenced to trimethyl phosphate (TMP) (δ( 31 P) = 2.8 ppm).…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

See 2 more Smart Citations

Synthesis and Characterization of Poly(vinylphosphonic acid-co-acrylic acid) Copolymers for Application in Bone Tissue Scaffolds

Dey¹,

Zhong

Youle³

et al. 2016

Macromolecules

View full text Add to dashboard Cite

Poly(vinylphosphonic acid-co-acrylic acid) (PVPA-co-AA) has recently been identified as a possible candidate for use in bone tissue engineering. It is hypothesized that the strong binding of PVPA-co-AA to calcium in natural bone inhibits osteoclast activity. The free radical polymerization of acrylic acid (AA) with vinylphosphonic acid (VPA) has been investigated with varying experimental conditions. A range of copolymers were successfully produced and their compositions were determined quantitatively using 31P NMR spectroscopy. Monomer conversions were calculated using 1H NMR spectroscopy and a general decrease was found with increasing VPA content. Titration studies demonstrated an increase in the degree of dissociation as a function of VPA in the copolymer. However, a VPA content ca. 30 mol % was found to be the optimum for calcium chelation, suggesting that this composition is the most promising for biomaterials applications. Assessment of cell metabolic activity showed that PVPA-co-AA has no detrimental effect on cells, regardless of copolymer composition.

show abstract

Section: Resultssupporting

confidence: 93%

Section: ■ Results and Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis and Characterization of Poly(vinylphosphonic acid-co-acrylic acid) Copolymers for Application in Bone Tissue Scaffolds

Dey¹,

Zhong

Youle³

et al. 2016

Macromolecules

View full text Add to dashboard Cite

show abstract

“…Typically, the self-diffusion coefficients of the respective polymer signals at 4.8 ppm (CH-proton of the isopropylester) and between 2.8 and 1 ppm (reflecting the CH and CH 2 main chain signals as well as CH 3 the isopropylester), have to be in a similar value range as the starting DPE molecule. Due to the smaller diffusion coefficient of 10 À9.5 m 2 s À1 (log -D 9.5, cf.…”

Section: Poly(vinylphosphonic Acid)-homopolymersmentioning

confidence: 99%

“…[3] Though copolymers with styrene, obtained both via radical and anionic polymerization, were already reported by Hartmann et al [4] in 1980, the achieved conversion, yields and molecular weights of the statistical copolymers were rather low. The grafting onto other polymers has also been described by .…”

Section: Introductionmentioning

confidence: 99%

Vinylphosphonic Acid Homo‐ and Block Copolymers

Wagner

Manhart

Deniz

et al. 2009

Macro Chemistry & Physics

View full text Add to dashboard Cite

Vinylphosphonic acid homo‐ and block copolymers with styrene have been prepared via anionic polymerization of dialkylvinylphosphonates (VPE) and subsequent hydrolysis of the precursor polyester with trimethylsilylbromide. Poly(vinylphosphonic acid) (PVPA) homopolymers with 4 200<$\overline M _{\rm w}$<814 000 have been obtained with vinyl‐diisopropyl‐phosphonate as monomer. With polystyryl anion as macroinitiator, AB block copolymers have been obtained with block compositions from approximately 9:2 to 3:7; however, the total molecular weights are limited to <10 000, due to solubility limitations. 1H DOSY NMR has been used to prove a real block‐type structure consisting of hydrophobic polystyrene and hydrophilic PVPA (PVPA‐b‐PS), which exhibits a phase‐separated morphology. It was found that the bulk proton conductivity does not change significantly with different molecular weights of the homopolymers, but is strongly dependant on the composition of the block copolymers. PVPA‐b‐PS with low PS content, behaves more or less like PVPA homopolymers, whereas PVPA‐b‐PS with a high PS content looses its conductivity when heated above the glass transition temperature of the PS phase. The swelling behaviour of the block copolymers differs significantly from that of PVPA homopolymers, when exposed to a humidified environment.

show abstract