Some Observations on Iridium 192

Schaeflein, J. W.; Schlesinger, T.; Stephens, Sidney O.; Neblett, David; Haymond, Herman R.; Harwood, George E.

doi:10.1159/000400871

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Substitute radionuclides that offered an improvement of these toxicities included cobalt-60 ( 60 Co), cesium-137 ( 137 Cs), and iridium-192 ( 192 Ir). 6 These radionuclides generally possessed the following: 1) A high specific activity, meaning a high rate of radiation emissions per unit mass of the radionuclide.…”

Section: Introductionmentioning

confidence: 99%

A Proposed Methodology to Select Radioisotopes for Use in Radionuclide Therapy

Cuaron¹,

Hirsch²,

Medich³

et al. 2009

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

SUMMARY:The American Journal of Neuroradiology has played a seminal role in the history of vertebral augmentation (VA). Because VA is increasingly being included in the multidisciplinary management of malignant vertebral compression fractures (VCFs), combined therapeutic approaches that include strategies to treat metastatic disease along with the fracture have become appealing options for patients. To that end, we recently investigated the dosimetric feasibility of treating malignant VCFs with radionuclide therapy. The goal would be to provide local control of the systemic disease beyond the pain relief and structural support provided by polymethylmethacrylate cement. The purpose of this article is to propose a methodology for evaluating radionuclides for use in radiation therapy that takes into account a number of factors including radiation characteristics, biochemical effects, production capacity, and safety. The goal of such a methodology is to introduce a systematic approach to selecting radionuclides in designing treatment regimens and future investigations and also to stimulate discussion and experimentation involving new radionuclides that may provide more effective treatments than the current isotopes in widespread use.

show abstract

Section: Introductionmentioning

confidence: 99%